Anti-TPD52L1 monoclonal antibody

Pre-made anti-TPD52L1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to TPD52L1/TPD52L1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2774-Ab-1/ GM-Tg-hg-IP2774-Ab-2Anti-Human TPD52L1 monoclonal antibodyHuman
GM-Tg-rg-IP2774-Ab-1/ GM-Tg-rg-IP2774-Ab-2Anti-Rat TPD52L1 monoclonal antibodyRat
GM-Tg-mg-IP2774-Ab-1/ GM-Tg-mg-IP2774-Ab-2Anti-Mouse TPD52L1 monoclonal antibodyMouse
GM-Tg-cynog-IP2774-Ab-1/ GM-Tg-cynog-IP2774-Ab-2Anti-Cynomolgus/ Rhesus macaque TPD52L1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2774-Ab-1/ GM-Tg-felg-IP2774-Ab-2Anti-Feline TPD52L1 monoclonal antibodyFeline
GM-Tg-cang-IP2774-Ab-1/ GM-Tg-cang-IP2774-Ab-2Anti-Canine TPD52L1 monoclonal antibodyCanine
GM-Tg-bovg-IP2774-Ab-1/ GM-Tg-bovg-IP2774-Ab-2Anti-Bovine TPD52L1 monoclonal antibodyBovine
GM-Tg-equg-IP2774-Ab-1/ GM-Tg-equg-IP2774-Ab-2Anti-Equine TPD52L1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2774-Ab-1/ GM-Tg-hg-IP2774-Ab-2; GM-Tg-rg-IP2774-Ab-1/ GM-Tg-rg-IP2774-Ab-2;
GM-Tg-mg-IP2774-Ab-1/ GM-Tg-mg-IP2774-Ab-2; GM-Tg-cynog-IP2774-Ab-1/ GM-Tg-cynog-IP2774-Ab-2;
GM-Tg-felg-IP2774-Ab-1/ GM-Tg-felg-IP2774-Ab-2; GM-Tg-cang-IP2774-Ab-1/ GM-Tg-cang-IP2774-Ab-2;
GM-Tg-bovg-IP2774-Ab-1/ GM-Tg-bovg-IP2774-Ab-2; GM-Tg-equg-IP2774-Ab-1/ GM-Tg-equg-IP2774-Ab-2
Products NameAnti-TPD52L1 monoclonal antibody
Formatmab
Target NameTPD52L1
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-TPD52L1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2774-Ag-1Recombinant multi-species TPD53/ TPD52L1/ D53 protein


    Target information

    Target IDGM-IP2774
    Target NameTPD52L1
    Gene ID7164,21987,689256,716568,612660,101090108,534629,100073013
    Gene Symbol and SynonymsD53,TPD52L1,TPD53
    Uniprot AccessionQ16890
    Uniprot Entry NameTPD53_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseProstate Cancer
    Gene EnsemblENSG00000111907
    Target ClassificationN/A

    The target: TPD52L1, gene name: TPD52L1, also named as D53. This gene encodes a member of a family of proteins that contain coiled-coil domains and may form hetero- or homomers. The encoded protein is involved in cell proliferation and calcium signaling. It also interacts with the mitogen-activated protein kinase kinase kinase 5 (MAP3K5/ASK1) and positively regulates MAP3K5-induced apoptosis. Multiple alternatively spliced transcript variants have been observed. [provided by RefSeq, Jan 2016].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.