Anti-TRIML2 monoclonal antibody

Pre-made anti-TRIML2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to TRIML2/TRIML2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2782-Ab-1/ GM-Tg-hg-IP2782-Ab-2Anti-Human TRIML2 monoclonal antibodyHuman
GM-Tg-rg-IP2782-Ab-1/ GM-Tg-rg-IP2782-Ab-2Anti-Rat TRIML2 monoclonal antibodyRat
GM-Tg-mg-IP2782-Ab-1/ GM-Tg-mg-IP2782-Ab-2Anti-Mouse TRIML2 monoclonal antibodyMouse
GM-Tg-cynog-IP2782-Ab-1/ GM-Tg-cynog-IP2782-Ab-2Anti-Cynomolgus/ Rhesus macaque TRIML2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2782-Ab-1/ GM-Tg-felg-IP2782-Ab-2Anti-Feline TRIML2 monoclonal antibodyFeline
GM-Tg-cang-IP2782-Ab-1/ GM-Tg-cang-IP2782-Ab-2Anti-Canine TRIML2 monoclonal antibodyCanine
GM-Tg-bovg-IP2782-Ab-1/ GM-Tg-bovg-IP2782-Ab-2Anti-Bovine TRIML2 monoclonal antibodyBovine
GM-Tg-equg-IP2782-Ab-1/ GM-Tg-equg-IP2782-Ab-2Anti-Equine TRIML2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2782-Ab-1/ GM-Tg-hg-IP2782-Ab-2; GM-Tg-rg-IP2782-Ab-1/ GM-Tg-rg-IP2782-Ab-2;
GM-Tg-mg-IP2782-Ab-1/ GM-Tg-mg-IP2782-Ab-2; GM-Tg-cynog-IP2782-Ab-1/ GM-Tg-cynog-IP2782-Ab-2;
GM-Tg-felg-IP2782-Ab-1/ GM-Tg-felg-IP2782-Ab-2; GM-Tg-cang-IP2782-Ab-1/ GM-Tg-cang-IP2782-Ab-2;
GM-Tg-bovg-IP2782-Ab-1/ GM-Tg-bovg-IP2782-Ab-2; GM-Tg-equg-IP2782-Ab-1/ GM-Tg-equg-IP2782-Ab-2
Products NameAnti-TRIML2 monoclonal antibody
Formatmab
Target NameTRIML2
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-TRIML2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2782-Ag-1Recombinant multi-species TRIMM/ TRIML2/ SPRYD6 protein


    Target information

    Target IDGM-IP2782
    Target NameTRIML2
    Gene ID205860,622117,290766,707731,482902,101099545,520201,100055154
    Gene Symbol and SynonymsEG622117,RGD1565382,SPRYD6,TRIML2,Tu4
    Uniprot AccessionQ8N7C3
    Uniprot Entry NameTRIMM_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000179046
    Target ClassificationN/A

    The target: TRIML2, gene name: TRIML2, also named as SPRYD6. This gene encodes a member of the tri-partite motif (TRIM) family of proteins. This protein may be regulated by the tumor suppressor p53 and may regulate p53 through the enhancement of p53 SUMOylation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.