Anti-TTLL12 monoclonal antibody

Pre-made anti-TTLL12 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to TTLL12/TTLL12 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2789-Ab-1/ GM-Tg-hg-IP2789-Ab-2Anti-Human TTLL12 monoclonal antibodyHuman
GM-Tg-rg-IP2789-Ab-1/ GM-Tg-rg-IP2789-Ab-2Anti-Rat TTLL12 monoclonal antibodyRat
GM-Tg-mg-IP2789-Ab-1/ GM-Tg-mg-IP2789-Ab-2Anti-Mouse TTLL12 monoclonal antibodyMouse
GM-Tg-cynog-IP2789-Ab-1/ GM-Tg-cynog-IP2789-Ab-2Anti-Cynomolgus/ Rhesus macaque TTLL12 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2789-Ab-1/ GM-Tg-felg-IP2789-Ab-2Anti-Feline TTLL12 monoclonal antibodyFeline
GM-Tg-cang-IP2789-Ab-1/ GM-Tg-cang-IP2789-Ab-2Anti-Canine TTLL12 monoclonal antibodyCanine
GM-Tg-bovg-IP2789-Ab-1/ GM-Tg-bovg-IP2789-Ab-2Anti-Bovine TTLL12 monoclonal antibodyBovine
GM-Tg-equg-IP2789-Ab-1/ GM-Tg-equg-IP2789-Ab-2Anti-Equine TTLL12 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2789-Ab-1/ GM-Tg-hg-IP2789-Ab-2; GM-Tg-rg-IP2789-Ab-1/ GM-Tg-rg-IP2789-Ab-2;
GM-Tg-mg-IP2789-Ab-1/ GM-Tg-mg-IP2789-Ab-2; GM-Tg-cynog-IP2789-Ab-1/ GM-Tg-cynog-IP2789-Ab-2;
GM-Tg-felg-IP2789-Ab-1/ GM-Tg-felg-IP2789-Ab-2; GM-Tg-cang-IP2789-Ab-1/ GM-Tg-cang-IP2789-Ab-2;
GM-Tg-bovg-IP2789-Ab-1/ GM-Tg-bovg-IP2789-Ab-2; GM-Tg-equg-IP2789-Ab-1/ GM-Tg-equg-IP2789-Ab-2
Products NameAnti-TTLL12 monoclonal antibody
Formatmab
Target NameTTLL12
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-TTLL12 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2789-Ag-1Recombinant multi-species TTL12/ TTLL12/ dJ526I14.2 protein


    Target information

    Target IDGM-IP2789
    Target NameTTLL12
    Gene ID23170,223723,300105,714871,474474,101092376,511319,100071120
    Gene Symbol and SynonymsD430005B17,dJ526I14.2,RGD1305319,TTLL12
    Uniprot AccessionQ14166
    Uniprot Entry NameTTL12_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000100304
    Target ClassificationN/A

    The target: TTLL12, gene name: TTLL12, also named as dJ526I14.2. Enables H4K20me3 modified histone binding activity and tubulin binding activity. Involved in negative regulation of type I interferon-mediated signaling pathway and regulation of mitotic cell cycle. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.