Anti-TYW3 monoclonal antibody

Pre-made anti-TYW3 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to TYW3/TYW3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2791-Ab-1/ GM-Tg-hg-IP2791-Ab-2Anti-Human TYW3 monoclonal antibodyHuman
GM-Tg-rg-IP2791-Ab-1/ GM-Tg-rg-IP2791-Ab-2Anti-Rat TYW3 monoclonal antibodyRat
GM-Tg-mg-IP2791-Ab-1/ GM-Tg-mg-IP2791-Ab-2Anti-Mouse TYW3 monoclonal antibodyMouse
GM-Tg-cynog-IP2791-Ab-1/ GM-Tg-cynog-IP2791-Ab-2Anti-Cynomolgus/ Rhesus macaque TYW3 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2791-Ab-1/ GM-Tg-felg-IP2791-Ab-2Anti-Feline TYW3 monoclonal antibodyFeline
GM-Tg-cang-IP2791-Ab-1/ GM-Tg-cang-IP2791-Ab-2Anti-Canine TYW3 monoclonal antibodyCanine
GM-Tg-bovg-IP2791-Ab-1/ GM-Tg-bovg-IP2791-Ab-2Anti-Bovine TYW3 monoclonal antibodyBovine
GM-Tg-equg-IP2791-Ab-1/ GM-Tg-equg-IP2791-Ab-2Anti-Equine TYW3 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2791-Ab-1/ GM-Tg-hg-IP2791-Ab-2; GM-Tg-rg-IP2791-Ab-1/ GM-Tg-rg-IP2791-Ab-2;
GM-Tg-mg-IP2791-Ab-1/ GM-Tg-mg-IP2791-Ab-2; GM-Tg-cynog-IP2791-Ab-1/ GM-Tg-cynog-IP2791-Ab-2;
GM-Tg-felg-IP2791-Ab-1/ GM-Tg-felg-IP2791-Ab-2; GM-Tg-cang-IP2791-Ab-1/ GM-Tg-cang-IP2791-Ab-2;
GM-Tg-bovg-IP2791-Ab-1/ GM-Tg-bovg-IP2791-Ab-2; GM-Tg-equg-IP2791-Ab-1/ GM-Tg-equg-IP2791-Ab-2
Products NameAnti-TYW3 monoclonal antibody
Formatmab
Target NameTYW3
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-TYW3 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2791-Ag-1Recombinant multi-species TYW3/ C1orf171 protein


    Target information

    Target IDGM-IP2791
    Target NameTYW3
    Gene ID127253,209584,499731,704515,479986,101086328,519731,100053370
    Gene Symbol and Synonyms5230400J09Rik,C1orf171,RGD1559623,TYW3
    Uniprot AccessionQ6IPR3,Q5E9U4
    Uniprot Entry NameTYW3_HUMAN,TYW3_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000162623
    Target ClassificationN/A

    The target: TYW3, gene name: TYW3, also named as C1orf171. Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW3 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006).[supplied by OMIM, Mar 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.