Anti-VPS50 monoclonal antibody

Pre-made anti-VPS50 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to VPS50/VPS50 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2806-Ab-1/ GM-Tg-hg-IP2806-Ab-2Anti-Human VPS50 monoclonal antibodyHuman
GM-Tg-rg-IP2806-Ab-1/ GM-Tg-rg-IP2806-Ab-2Anti-Rat VPS50 monoclonal antibodyRat
GM-Tg-mg-IP2806-Ab-1/ GM-Tg-mg-IP2806-Ab-2Anti-Mouse VPS50 monoclonal antibodyMouse
GM-Tg-cynog-IP2806-Ab-1/ GM-Tg-cynog-IP2806-Ab-2Anti-Cynomolgus/ Rhesus macaque VPS50 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2806-Ab-1/ GM-Tg-felg-IP2806-Ab-2Anti-Feline VPS50 monoclonal antibodyFeline
GM-Tg-cang-IP2806-Ab-1/ GM-Tg-cang-IP2806-Ab-2Anti-Canine VPS50 monoclonal antibodyCanine
GM-Tg-bovg-IP2806-Ab-1/ GM-Tg-bovg-IP2806-Ab-2Anti-Bovine VPS50 monoclonal antibodyBovine
GM-Tg-equg-IP2806-Ab-1/ GM-Tg-equg-IP2806-Ab-2Anti-Equine VPS50 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2806-Ab-1/ GM-Tg-hg-IP2806-Ab-2; GM-Tg-rg-IP2806-Ab-1/ GM-Tg-rg-IP2806-Ab-2;
GM-Tg-mg-IP2806-Ab-1/ GM-Tg-mg-IP2806-Ab-2; GM-Tg-cynog-IP2806-Ab-1/ GM-Tg-cynog-IP2806-Ab-2;
GM-Tg-felg-IP2806-Ab-1/ GM-Tg-felg-IP2806-Ab-2; GM-Tg-cang-IP2806-Ab-1/ GM-Tg-cang-IP2806-Ab-2;
GM-Tg-bovg-IP2806-Ab-1/ GM-Tg-bovg-IP2806-Ab-2; GM-Tg-equg-IP2806-Ab-1/ GM-Tg-equg-IP2806-Ab-2
Products NameAnti-VPS50 monoclonal antibody
Formatmab
Target NameVPS50
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-VPS50 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2806-Ag-1Recombinant multi-species VPS50/ CCDC132/ VPS54L protein
    ORF Viral VectorpGMLPm003635mouse Vps50 Lentivirus plasmid
    ORF Viral VectorvGMLPm003635mouse Vps50 Lentivirus particle


    Target information

    Target IDGM-IP2806
    Target NameVPS50
    Gene ID55610,73288,312083,701991,475228,101093508,535248,100051289
    Gene Symbol and Synonyms1700034M03Rik,8430415E05Rik,BLM,CCDC132,mKIAA1861,NEDMSC,RGD1304751,VPS50,VPS54L
    Uniprot AccessionQ96JG6,F1LSG8
    Uniprot Entry NameVPS50_HUMAN,VPS50_RAT
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000004766
    Target ClassificationN/A

    The target: VPS50, gene name: VPS50, also named as CCDC132, VPS54L. Enables SNARE binding activity. Acts upstream of or within endocytic recycling. Located in recycling endosome. Part of EARP complex. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.