Anti-WDR66 monoclonal antibody

Pre-made anti-WDR66 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to WDR66/WDR66 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2812-Ab-1/ GM-Tg-hg-IP2812-Ab-2Anti-Human WDR66 monoclonal antibodyHuman
GM-Tg-rg-IP2812-Ab-1/ GM-Tg-rg-IP2812-Ab-2Anti-Rat WDR66 monoclonal antibodyRat
GM-Tg-mg-IP2812-Ab-1/ GM-Tg-mg-IP2812-Ab-2Anti-Mouse WDR66 monoclonal antibodyMouse
GM-Tg-cynog-IP2812-Ab-1/ GM-Tg-cynog-IP2812-Ab-2Anti-Cynomolgus/ Rhesus macaque WDR66 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2812-Ab-1/ GM-Tg-felg-IP2812-Ab-2Anti-Feline WDR66 monoclonal antibodyFeline
GM-Tg-cang-IP2812-Ab-1/ GM-Tg-cang-IP2812-Ab-2Anti-Canine WDR66 monoclonal antibodyCanine
GM-Tg-bovg-IP2812-Ab-1/ GM-Tg-bovg-IP2812-Ab-2Anti-Bovine WDR66 monoclonal antibodyBovine
GM-Tg-equg-IP2812-Ab-1/ GM-Tg-equg-IP2812-Ab-2Anti-Equine WDR66 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2812-Ab-1/ GM-Tg-hg-IP2812-Ab-2; GM-Tg-rg-IP2812-Ab-1/ GM-Tg-rg-IP2812-Ab-2;
GM-Tg-mg-IP2812-Ab-1/ GM-Tg-mg-IP2812-Ab-2; GM-Tg-cynog-IP2812-Ab-1/ GM-Tg-cynog-IP2812-Ab-2;
GM-Tg-felg-IP2812-Ab-1/ GM-Tg-felg-IP2812-Ab-2; GM-Tg-cang-IP2812-Ab-1/ GM-Tg-cang-IP2812-Ab-2;
GM-Tg-bovg-IP2812-Ab-1/ GM-Tg-bovg-IP2812-Ab-2; GM-Tg-equg-IP2812-Ab-1/ GM-Tg-equg-IP2812-Ab-2
Products NameAnti-WDR66 monoclonal antibody
Formatmab
Target NameWDR66
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-WDR66 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2812-Ag-1Recombinant multi-species CF251/ WDR66/ CFAP251 protein


    Target information

    Target IDGM-IP2812
    Target NameWDR66
    Gene ID144406,269701,304498,701061,477466,101096173,536738,100059883
    Gene Symbol and Synonyms4930415N18Rik,4933428F06Rik,5031404N07,CaM-IP4,CFAP251,RGD1564948,SPGF33,WDR66
    Uniprot AccessionQ8TBY9
    Uniprot Entry NameCF251_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000158023
    Target ClassificationN/A

    The target: WDR66, gene name: WDR66, also named as CFAP251, CaM-IP4. This protein encoded by this gene belongs to the WD repeat-containing family of proteins, which function in the formation of protein-protein complexes in a variety of biological pathways. This family member appears to function in the determination of mean platelet volume (MPV), and polymorphisms in this gene have been associated with variance in MPV. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.