Anti-XIRP1 monoclonal antibody

Pre-made anti-XIRP1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to XIRP1/XIRP1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2814-Ab-1/ GM-Tg-hg-IP2814-Ab-2Anti-Human XIRP1 monoclonal antibodyHuman
GM-Tg-rg-IP2814-Ab-1/ GM-Tg-rg-IP2814-Ab-2Anti-Rat XIRP1 monoclonal antibodyRat
GM-Tg-mg-IP2814-Ab-1/ GM-Tg-mg-IP2814-Ab-2Anti-Mouse XIRP1 monoclonal antibodyMouse
GM-Tg-cynog-IP2814-Ab-1/ GM-Tg-cynog-IP2814-Ab-2Anti-Cynomolgus/ Rhesus macaque XIRP1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2814-Ab-1/ GM-Tg-felg-IP2814-Ab-2Anti-Feline XIRP1 monoclonal antibodyFeline
GM-Tg-cang-IP2814-Ab-1/ GM-Tg-cang-IP2814-Ab-2Anti-Canine XIRP1 monoclonal antibodyCanine
GM-Tg-bovg-IP2814-Ab-1/ GM-Tg-bovg-IP2814-Ab-2Anti-Bovine XIRP1 monoclonal antibodyBovine
GM-Tg-equg-IP2814-Ab-1/ GM-Tg-equg-IP2814-Ab-2Anti-Equine XIRP1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2814-Ab-1/ GM-Tg-hg-IP2814-Ab-2; GM-Tg-rg-IP2814-Ab-1/ GM-Tg-rg-IP2814-Ab-2;
GM-Tg-mg-IP2814-Ab-1/ GM-Tg-mg-IP2814-Ab-2; GM-Tg-cynog-IP2814-Ab-1/ GM-Tg-cynog-IP2814-Ab-2;
GM-Tg-felg-IP2814-Ab-1/ GM-Tg-felg-IP2814-Ab-2; GM-Tg-cang-IP2814-Ab-1/ GM-Tg-cang-IP2814-Ab-2;
GM-Tg-bovg-IP2814-Ab-1/ GM-Tg-bovg-IP2814-Ab-2; GM-Tg-equg-IP2814-Ab-1/ GM-Tg-equg-IP2814-Ab-2
Products NameAnti-XIRP1 monoclonal antibody
Formatmab
Target NameXIRP1
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-XIRP1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2814-Ag-1Recombinant multi-species XIRP1/ CMYA1/ Xin protein


    Target information

    Target IDGM-IP2814
    Target NameXIRP1
    Gene ID165904,22437,100910104,694199,485597,101084568,509670,100055451
    Gene Symbol and SynonymsCMYA1,Xin,XIRP1
    Uniprot AccessionQ702N8
    Uniprot Entry NameXIRP1_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000168334
    Target ClassificationN/A

    The target: XIRP1, gene name: XIRP1, also named as CMYA1, Xin. The protein encoded by this gene is a striated muscle protein and belongs to the Xin actin-binding repeat-containing protein (XIRP) family. The protein functions to protect actin filaments during depolymerization. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2017].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.