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Anti-CCDC50 monoclonal antibody
Pre-made anti-CCDC50 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to CCDC50/CCDC50 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP2870-Ab-1/ GM-Tg-hg-IP2870-Ab-2 | Anti-Human CCDC50 monoclonal antibody | Human |
| GM-Tg-rg-IP2870-Ab-1/ GM-Tg-rg-IP2870-Ab-2 | Anti-Rat CCDC50 monoclonal antibody | Rat |
| GM-Tg-mg-IP2870-Ab-1/ GM-Tg-mg-IP2870-Ab-2 | Anti-Mouse CCDC50 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP2870-Ab-1/ GM-Tg-cynog-IP2870-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CCDC50 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP2870-Ab-1/ GM-Tg-felg-IP2870-Ab-2 | Anti-Feline CCDC50 monoclonal antibody | Feline |
| GM-Tg-cang-IP2870-Ab-1/ GM-Tg-cang-IP2870-Ab-2 | Anti-Canine CCDC50 monoclonal antibody | Canine |
| GM-Tg-bovg-IP2870-Ab-1/ GM-Tg-bovg-IP2870-Ab-2 | Anti-Bovine CCDC50 monoclonal antibody | Bovine |
| GM-Tg-equg-IP2870-Ab-1/ GM-Tg-equg-IP2870-Ab-2 | Anti-Equine CCDC50 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP2870-Ab-1/ GM-Tg-hg-IP2870-Ab-2; GM-Tg-rg-IP2870-Ab-1/ GM-Tg-rg-IP2870-Ab-2; GM-Tg-mg-IP2870-Ab-1/ GM-Tg-mg-IP2870-Ab-2; GM-Tg-cynog-IP2870-Ab-1/ GM-Tg-cynog-IP2870-Ab-2; GM-Tg-felg-IP2870-Ab-1/ GM-Tg-felg-IP2870-Ab-2; GM-Tg-cang-IP2870-Ab-1/ GM-Tg-cang-IP2870-Ab-2; GM-Tg-bovg-IP2870-Ab-1/ GM-Tg-bovg-IP2870-Ab-2; GM-Tg-equg-IP2870-Ab-1/ GM-Tg-equg-IP2870-Ab-2 |
| Products Name | Anti-CCDC50 monoclonal antibody |
| Format | mab |
| Target Name | CCDC50 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-CCDC50 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP2870-Ag-1 | Recombinant multi-species CCD50/ CCDC50/ C3orf6 protein |
Target information
| Target ID | GM-IP2870 |
| Target Name | CCDC50 |
| Gene ID | 152137,67501,288022,705459,478675,101080475,529404,100068861 |
| Gene Symbol and Synonyms | C3orf6,C3orf6h,CCDC50,DFNA44,YMER |
| Uniprot Accession | Q8IVM0,Q810U0 |
| Uniprot Entry Name | CCD50_HUMAN,CCD50_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000152492 |
| Target Classification | N/A |
The target: CCDC50, gene name: CCDC50, also named as C3orf6, DFNA44, YMER. This gene encodes a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF)-mediated cell signaling. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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