Anti-PHETA1 monoclonal antibody

Pre-made anti-PHETA1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to PHETA1/PHETA1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2877-Ab-1/ GM-Tg-hg-IP2877-Ab-2Anti-Human PHETA1 monoclonal antibodyHuman
GM-Tg-rg-IP2877-Ab-1/ GM-Tg-rg-IP2877-Ab-2Anti-Rat PHETA1 monoclonal antibodyRat
GM-Tg-mg-IP2877-Ab-1/ GM-Tg-mg-IP2877-Ab-2Anti-Mouse PHETA1 monoclonal antibodyMouse
GM-Tg-cynog-IP2877-Ab-1/ GM-Tg-cynog-IP2877-Ab-2Anti-Cynomolgus/ Rhesus macaque PHETA1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2877-Ab-1/ GM-Tg-felg-IP2877-Ab-2Anti-Feline PHETA1 monoclonal antibodyFeline
GM-Tg-cang-IP2877-Ab-1/ GM-Tg-cang-IP2877-Ab-2Anti-Canine PHETA1 monoclonal antibodyCanine
GM-Tg-bovg-IP2877-Ab-1/ GM-Tg-bovg-IP2877-Ab-2Anti-Bovine PHETA1 monoclonal antibodyBovine
GM-Tg-equg-IP2877-Ab-1/ GM-Tg-equg-IP2877-Ab-2Anti-Equine PHETA1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2877-Ab-1/ GM-Tg-hg-IP2877-Ab-2; GM-Tg-rg-IP2877-Ab-1/ GM-Tg-rg-IP2877-Ab-2;
GM-Tg-mg-IP2877-Ab-1/ GM-Tg-mg-IP2877-Ab-2; GM-Tg-cynog-IP2877-Ab-1/ GM-Tg-cynog-IP2877-Ab-2;
GM-Tg-felg-IP2877-Ab-1/ GM-Tg-felg-IP2877-Ab-2; GM-Tg-cang-IP2877-Ab-1/ GM-Tg-cang-IP2877-Ab-2;
GM-Tg-bovg-IP2877-Ab-1/ GM-Tg-bovg-IP2877-Ab-2; GM-Tg-equg-IP2877-Ab-1/ GM-Tg-equg-IP2877-Ab-2
Products NameAnti-PHETA1 monoclonal antibody
Formatmab
Target NamePHETA1
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-PHETA1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2877-Ag-1Recombinant multi-species SESQ1/ PHETA1/ FAM109A protein


    Target information

    Target IDGM-IP2877
    Target NamePHETA1
    Gene ID144717,231717,288664,710475,486268,102900969,107131393,102150096
    Gene Symbol and SynonymsA230106M15Rik,FAM109A,IPIP27A,PHETA1,RGD1310656,SES1
    Uniprot AccessionQ8N4B1,D3ZL52
    Uniprot Entry NameSESQ1_HUMAN,SESQ1_RAT
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000198324
    Target ClassificationN/A

    The target: PHETA1, gene name: PHETA1, also named as FAM109A, IPIP27A, SES1. This gene encodes a protein that localizes to the endosome and interacts with the enzyme, inositol polyphosphate 5-phosphatase OCRL-1. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.