Anti-MDM1 monoclonal antibody

Pre-made anti-MDM1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to MDM1/MDM1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2894-Ab-1/ GM-Tg-hg-IP2894-Ab-2Anti-Human MDM1 monoclonal antibodyHuman
GM-Tg-rg-IP2894-Ab-1/ GM-Tg-rg-IP2894-Ab-2Anti-Rat MDM1 monoclonal antibodyRat
GM-Tg-mg-IP2894-Ab-1/ GM-Tg-mg-IP2894-Ab-2Anti-Mouse MDM1 monoclonal antibodyMouse
GM-Tg-cynog-IP2894-Ab-1/ GM-Tg-cynog-IP2894-Ab-2Anti-Cynomolgus/ Rhesus macaque MDM1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2894-Ab-1/ GM-Tg-felg-IP2894-Ab-2Anti-Feline MDM1 monoclonal antibodyFeline
GM-Tg-cang-IP2894-Ab-1/ GM-Tg-cang-IP2894-Ab-2Anti-Canine MDM1 monoclonal antibodyCanine
GM-Tg-bovg-IP2894-Ab-1/ GM-Tg-bovg-IP2894-Ab-2Anti-Bovine MDM1 monoclonal antibodyBovine
GM-Tg-equg-IP2894-Ab-1/ GM-Tg-equg-IP2894-Ab-2Anti-Equine MDM1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2894-Ab-1/ GM-Tg-hg-IP2894-Ab-2; GM-Tg-rg-IP2894-Ab-1/ GM-Tg-rg-IP2894-Ab-2;
GM-Tg-mg-IP2894-Ab-1/ GM-Tg-mg-IP2894-Ab-2; GM-Tg-cynog-IP2894-Ab-1/ GM-Tg-cynog-IP2894-Ab-2;
GM-Tg-felg-IP2894-Ab-1/ GM-Tg-felg-IP2894-Ab-2; GM-Tg-cang-IP2894-Ab-1/ GM-Tg-cang-IP2894-Ab-2;
GM-Tg-bovg-IP2894-Ab-1/ GM-Tg-bovg-IP2894-Ab-2; GM-Tg-equg-IP2894-Ab-1/ GM-Tg-equg-IP2894-Ab-2
Products NameAnti-MDM1 monoclonal antibody
Formatmab
Target NameMDM1
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-MDM1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2894-Ag-1Recombinant multi-species MDM1 protein


    Target information

    Target IDGM-IP2894
    Target NameMDM1
    Gene ID56890,17245,314859,718062,474439,101095425,614357,100051965
    Gene Symbol and SynonymsArrd2,Mdm-1,MDM1
    Uniprot AccessionQ8TC05,Q5PQN4
    Uniprot Entry NameMDM1_HUMAN,MDM1_RAT
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseDent disease
    Gene EnsemblENSG00000111554
    Target ClassificationN/A

    The target: MDM1, gene name: MDM1, also named as . This gene encodes a microtubule-binding nuclear protein that localizes to the centrioles of dividing cells and differentiating multiciliated cells and negatively regulates centriole duplication. The encoded protein is closely associated with the centriole barrel, and resides in the centriole lumen. Naturally-occurring mutations in the orthologous mouse gene are associated with age-related retinal degeneration. [provided by RefSeq, Feb 2019].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.