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Anti-NAT8B monoclonal antibody
Pre-made anti-NAT8B monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to NAT8B/NAT8B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP2896-Ab-1/ GM-Tg-hg-IP2896-Ab-2 | Anti-Human NAT8B monoclonal antibody | Human |
| GM-Tg-rg-IP2896-Ab-1/ GM-Tg-rg-IP2896-Ab-2 | Anti-Rat NAT8B monoclonal antibody | Rat |
| GM-Tg-mg-IP2896-Ab-1/ GM-Tg-mg-IP2896-Ab-2 | Anti-Mouse NAT8B monoclonal antibody | Mouse |
| GM-Tg-cynog-IP2896-Ab-1/ GM-Tg-cynog-IP2896-Ab-2 | Anti-Cynomolgus/ Rhesus macaque NAT8B monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP2896-Ab-1/ GM-Tg-felg-IP2896-Ab-2 | Anti-Feline NAT8B monoclonal antibody | Feline |
| GM-Tg-cang-IP2896-Ab-1/ GM-Tg-cang-IP2896-Ab-2 | Anti-Canine NAT8B monoclonal antibody | Canine |
| GM-Tg-bovg-IP2896-Ab-1/ GM-Tg-bovg-IP2896-Ab-2 | Anti-Bovine NAT8B monoclonal antibody | Bovine |
| GM-Tg-equg-IP2896-Ab-1/ GM-Tg-equg-IP2896-Ab-2 | Anti-Equine NAT8B monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP2896-Ab-1/ GM-Tg-hg-IP2896-Ab-2; GM-Tg-rg-IP2896-Ab-1/ GM-Tg-rg-IP2896-Ab-2; GM-Tg-mg-IP2896-Ab-1/ GM-Tg-mg-IP2896-Ab-2; GM-Tg-cynog-IP2896-Ab-1/ GM-Tg-cynog-IP2896-Ab-2; GM-Tg-felg-IP2896-Ab-1/ GM-Tg-felg-IP2896-Ab-2; GM-Tg-cang-IP2896-Ab-1/ GM-Tg-cang-IP2896-Ab-2; GM-Tg-bovg-IP2896-Ab-1/ GM-Tg-bovg-IP2896-Ab-2; GM-Tg-equg-IP2896-Ab-1/ GM-Tg-equg-IP2896-Ab-2 |
| Products Name | Anti-NAT8B monoclonal antibody |
| Format | mab |
| Target Name | NAT8B |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-NAT8B monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP2896-Ag-1 | Recombinant multi-species NAT8B/ CML2/ Hcml2P protein |
Target information
| Target ID | GM-IP2896 |
| Target Name | NAT8B |
| Gene ID | 51471 |
| Gene Symbol and Synonyms | CML2,Hcml2,NAT8B,NAT8BP |
| Uniprot Accession | Q9UHF3 |
| Uniprot Entry Name | NAT8B_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000204872 |
| Target Classification | N/A |
The target: NAT8B, gene name: NAT8B, also named as CML2, Hcml2P, NAT8B. This gene is highly similar to the N-acetyltransferase 8 (NAT8) gene which encodes a kidney and liver protein with homology to bacterial acetyltransferases involved in drug resistance. This gene is localized on chromosome 2 in the vicinity of the NAT8 gene and represents a human-specific transcribed pseudogene of NAT8. This gene contains two common polymorphic nonsense mutations that disrupt the active site of the protein. In the extremely rare event when both nonsense mutations are absent, the predicted protein would contain a complete acetyltransferase domain and would be identical in length to NAT8. [provided by RefSeq, Apr 2022].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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