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Anti-NBPF8 monoclonal antibody
Pre-made anti-NBPF8 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to NBPF8/NBPF8 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP2897-Ab-1/ GM-Tg-hg-IP2897-Ab-2 | Anti-Human NBPF8 monoclonal antibody | Human |
| GM-Tg-rg-IP2897-Ab-1/ GM-Tg-rg-IP2897-Ab-2 | Anti-Rat NBPF8 monoclonal antibody | Rat |
| GM-Tg-mg-IP2897-Ab-1/ GM-Tg-mg-IP2897-Ab-2 | Anti-Mouse NBPF8 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP2897-Ab-1/ GM-Tg-cynog-IP2897-Ab-2 | Anti-Cynomolgus/ Rhesus macaque NBPF8 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP2897-Ab-1/ GM-Tg-felg-IP2897-Ab-2 | Anti-Feline NBPF8 monoclonal antibody | Feline |
| GM-Tg-cang-IP2897-Ab-1/ GM-Tg-cang-IP2897-Ab-2 | Anti-Canine NBPF8 monoclonal antibody | Canine |
| GM-Tg-bovg-IP2897-Ab-1/ GM-Tg-bovg-IP2897-Ab-2 | Anti-Bovine NBPF8 monoclonal antibody | Bovine |
| GM-Tg-equg-IP2897-Ab-1/ GM-Tg-equg-IP2897-Ab-2 | Anti-Equine NBPF8 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP2897-Ab-1/ GM-Tg-hg-IP2897-Ab-2; GM-Tg-rg-IP2897-Ab-1/ GM-Tg-rg-IP2897-Ab-2; GM-Tg-mg-IP2897-Ab-1/ GM-Tg-mg-IP2897-Ab-2; GM-Tg-cynog-IP2897-Ab-1/ GM-Tg-cynog-IP2897-Ab-2; GM-Tg-felg-IP2897-Ab-1/ GM-Tg-felg-IP2897-Ab-2; GM-Tg-cang-IP2897-Ab-1/ GM-Tg-cang-IP2897-Ab-2; GM-Tg-bovg-IP2897-Ab-1/ GM-Tg-bovg-IP2897-Ab-2; GM-Tg-equg-IP2897-Ab-1/ GM-Tg-equg-IP2897-Ab-2 |
| Products Name | Anti-NBPF8 monoclonal antibody |
| Format | mab |
| Target Name | NBPF8 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-NBPF8 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP2897-Ag-1 | Recombinant multi-species NBPF8/ NBPF8P protein |
Target information
| Target ID | GM-IP2897 |
| Target Name | NBPF8 |
| Gene ID | 728841 |
| Gene Symbol and Synonyms | NBPF8,NBPF8P |
| Uniprot Accession | Q3BBV2 |
| Uniprot Entry Name | NBPF8_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000270231 |
| Target Classification | N/A |
The target: NBPF8, gene name: NBPF8, also named as NBPF8P. This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number variations in the human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, cognitive disability, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This gene family contains numerous pseudogenes. [provided by RefSeq, Apr 2013].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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