Anti-NSUN3 monoclonal antibody

Pre-made anti-NSUN3 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to NSUN3/NSUN3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2899-Ab-1/ GM-Tg-hg-IP2899-Ab-2Anti-Human NSUN3 monoclonal antibodyHuman
GM-Tg-rg-IP2899-Ab-1/ GM-Tg-rg-IP2899-Ab-2Anti-Rat NSUN3 monoclonal antibodyRat
GM-Tg-mg-IP2899-Ab-1/ GM-Tg-mg-IP2899-Ab-2Anti-Mouse NSUN3 monoclonal antibodyMouse
GM-Tg-cynog-IP2899-Ab-1/ GM-Tg-cynog-IP2899-Ab-2Anti-Cynomolgus/ Rhesus macaque NSUN3 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2899-Ab-1/ GM-Tg-felg-IP2899-Ab-2Anti-Feline NSUN3 monoclonal antibodyFeline
GM-Tg-cang-IP2899-Ab-1/ GM-Tg-cang-IP2899-Ab-2Anti-Canine NSUN3 monoclonal antibodyCanine
GM-Tg-bovg-IP2899-Ab-1/ GM-Tg-bovg-IP2899-Ab-2Anti-Bovine NSUN3 monoclonal antibodyBovine
GM-Tg-equg-IP2899-Ab-1/ GM-Tg-equg-IP2899-Ab-2Anti-Equine NSUN3 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2899-Ab-1/ GM-Tg-hg-IP2899-Ab-2; GM-Tg-rg-IP2899-Ab-1/ GM-Tg-rg-IP2899-Ab-2;
GM-Tg-mg-IP2899-Ab-1/ GM-Tg-mg-IP2899-Ab-2; GM-Tg-cynog-IP2899-Ab-1/ GM-Tg-cynog-IP2899-Ab-2;
GM-Tg-felg-IP2899-Ab-1/ GM-Tg-felg-IP2899-Ab-2; GM-Tg-cang-IP2899-Ab-1/ GM-Tg-cang-IP2899-Ab-2;
GM-Tg-bovg-IP2899-Ab-1/ GM-Tg-bovg-IP2899-Ab-2; GM-Tg-equg-IP2899-Ab-1/ GM-Tg-equg-IP2899-Ab-2
Products NameAnti-NSUN3 monoclonal antibody
Formatmab
Target NameNSUN3
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-NSUN3 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2899-Ag-1Recombinant multi-species NSUN3/ MST077/ MSTP077 protein


    Target information

    Target IDGM-IP2899
    Target NameNSUN3
    Gene ID63899,106338,100360437,106996137,607320,101081569,533791,100072898
    Gene Symbol and Synonyms6720484A09Rik,COXPD48,MST077,MSTP077,NSUN3
    Uniprot AccessionQ9H649,Q0P5D8
    Uniprot Entry NameNSUN3_HUMAN,NSUN3_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000178694
    Target ClassificationN/A

    The target: NSUN3, gene name: NSUN3, also named as MST077, MSTP077. Enables tRNA (cytosine-5-)-methyltransferase activity. Involved in regulation of mitochondrial translation and tRNA wobble base cytosine methylation. Located in mitochondrial matrix. Implicated in combined oxidative phosphorylation deficiency 48. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.