Anti-PLEKHB2 monoclonal antibody

Pre-made anti-PLEKHB2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to PLEKHB2/PLEKHB2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2904-Ab-1/ GM-Tg-hg-IP2904-Ab-2Anti-Human PLEKHB2 monoclonal antibodyHuman
GM-Tg-rg-IP2904-Ab-1/ GM-Tg-rg-IP2904-Ab-2Anti-Rat PLEKHB2 monoclonal antibodyRat
GM-Tg-mg-IP2904-Ab-1/ GM-Tg-mg-IP2904-Ab-2Anti-Mouse PLEKHB2 monoclonal antibodyMouse
GM-Tg-cynog-IP2904-Ab-1/ GM-Tg-cynog-IP2904-Ab-2Anti-Cynomolgus/ Rhesus macaque PLEKHB2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2904-Ab-1/ GM-Tg-felg-IP2904-Ab-2Anti-Feline PLEKHB2 monoclonal antibodyFeline
GM-Tg-cang-IP2904-Ab-1/ GM-Tg-cang-IP2904-Ab-2Anti-Canine PLEKHB2 monoclonal antibodyCanine
GM-Tg-bovg-IP2904-Ab-1/ GM-Tg-bovg-IP2904-Ab-2Anti-Bovine PLEKHB2 monoclonal antibodyBovine
GM-Tg-equg-IP2904-Ab-1/ GM-Tg-equg-IP2904-Ab-2Anti-Equine PLEKHB2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2904-Ab-1/ GM-Tg-hg-IP2904-Ab-2; GM-Tg-rg-IP2904-Ab-1/ GM-Tg-rg-IP2904-Ab-2;
GM-Tg-mg-IP2904-Ab-1/ GM-Tg-mg-IP2904-Ab-2; GM-Tg-cynog-IP2904-Ab-1/ GM-Tg-cynog-IP2904-Ab-2;
GM-Tg-felg-IP2904-Ab-1/ GM-Tg-felg-IP2904-Ab-2; GM-Tg-cang-IP2904-Ab-1/ GM-Tg-cang-IP2904-Ab-2;
GM-Tg-bovg-IP2904-Ab-1/ GM-Tg-bovg-IP2904-Ab-2; GM-Tg-equg-IP2904-Ab-1/ GM-Tg-equg-IP2904-Ab-2
Products NameAnti-PLEKHB2 monoclonal antibody
Formatmab
Target NamePLEKHB2
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-PLEKHB2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2904-Ag-1Recombinant multi-species PKHB2/ PLEKHB2/ EVT2 protein


    Target information

    Target IDGM-IP2904
    Target NamePLEKHB2
    Gene ID55041,226971,301337,718985,483858,101090283,783000,100068341
    Gene Symbol and Synonyms2310009M15Rik,evt-2,EVT2,Phdc,PLEKHB2
    Uniprot AccessionQ96CS7
    Uniprot Entry NamePKHB2_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000115762
    Target ClassificationN/A

    The target: PLEKHB2, gene name: PLEKHB2, also named as EVT2. Enables phosphatidylinositol-3,4,5-trisphosphate binding activity. Predicted to be involved in regulation of cell differentiation. Predicted to be located in recycling endosome membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.