Anti-SETD1B monoclonal antibody

Pre-made anti-SETD1B monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to SETD1B/SETD1B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2909-Ab-1/ GM-Tg-hg-IP2909-Ab-2Anti-Human SETD1B monoclonal antibodyHuman
GM-Tg-rg-IP2909-Ab-1/ GM-Tg-rg-IP2909-Ab-2Anti-Rat SETD1B monoclonal antibodyRat
GM-Tg-mg-IP2909-Ab-1/ GM-Tg-mg-IP2909-Ab-2Anti-Mouse SETD1B monoclonal antibodyMouse
GM-Tg-cynog-IP2909-Ab-1/ GM-Tg-cynog-IP2909-Ab-2Anti-Cynomolgus/ Rhesus macaque SETD1B monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2909-Ab-1/ GM-Tg-felg-IP2909-Ab-2Anti-Feline SETD1B monoclonal antibodyFeline
GM-Tg-cang-IP2909-Ab-1/ GM-Tg-cang-IP2909-Ab-2Anti-Canine SETD1B monoclonal antibodyCanine
GM-Tg-bovg-IP2909-Ab-1/ GM-Tg-bovg-IP2909-Ab-2Anti-Bovine SETD1B monoclonal antibodyBovine
GM-Tg-equg-IP2909-Ab-1/ GM-Tg-equg-IP2909-Ab-2Anti-Equine SETD1B monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2909-Ab-1/ GM-Tg-hg-IP2909-Ab-2; GM-Tg-rg-IP2909-Ab-1/ GM-Tg-rg-IP2909-Ab-2;
GM-Tg-mg-IP2909-Ab-1/ GM-Tg-mg-IP2909-Ab-2; GM-Tg-cynog-IP2909-Ab-1/ GM-Tg-cynog-IP2909-Ab-2;
GM-Tg-felg-IP2909-Ab-1/ GM-Tg-felg-IP2909-Ab-2; GM-Tg-cang-IP2909-Ab-1/ GM-Tg-cang-IP2909-Ab-2;
GM-Tg-bovg-IP2909-Ab-1/ GM-Tg-bovg-IP2909-Ab-2; GM-Tg-equg-IP2909-Ab-1/ GM-Tg-equg-IP2909-Ab-2
Products NameAnti-SETD1B monoclonal antibody
Formatmab
Target NameSETD1B
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-SETD1B monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2909-Ag-1Recombinant multi-species SET1B/ SETD1B/ KMT2G protein


    Target information

    Target IDGM-IP2909
    Target NameSETD1B
    Gene ID23067,208043,100359816,703717,486257,101096419,514102,100146430
    Gene Symbol and SynonymsIDDSELD,KMT2G,mKIAA1076,Set1B,SETD1B
    Uniprot AccessionQ9UPS6
    Uniprot Entry NameSET1B_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseCancer
    Gene EnsemblENSG00000139718
    Target ClassificationTumor-associated antigen (TAA)

    The target: SETD1B, gene name: SETD1B, also named as KMT2G, Set1B. SET1B is a component of a histone methyltransferase complex that produces trimethylated histone H3 at Lys4 (Lee et al., 2007 [PubMed 17355966]).[supplied by OMIM, Mar 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.