Anti-TSPYL5 monoclonal antibody

Pre-made anti-TSPYL5 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to TSPYL5/TSPYL5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2919-Ab-1/ GM-Tg-hg-IP2919-Ab-2Anti-Human TSPYL5 monoclonal antibodyHuman
GM-Tg-rg-IP2919-Ab-1/ GM-Tg-rg-IP2919-Ab-2Anti-Rat TSPYL5 monoclonal antibodyRat
GM-Tg-mg-IP2919-Ab-1/ GM-Tg-mg-IP2919-Ab-2Anti-Mouse TSPYL5 monoclonal antibodyMouse
GM-Tg-cynog-IP2919-Ab-1/ GM-Tg-cynog-IP2919-Ab-2Anti-Cynomolgus/ Rhesus macaque TSPYL5 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2919-Ab-1/ GM-Tg-felg-IP2919-Ab-2Anti-Feline TSPYL5 monoclonal antibodyFeline
GM-Tg-cang-IP2919-Ab-1/ GM-Tg-cang-IP2919-Ab-2Anti-Canine TSPYL5 monoclonal antibodyCanine
GM-Tg-bovg-IP2919-Ab-1/ GM-Tg-bovg-IP2919-Ab-2Anti-Bovine TSPYL5 monoclonal antibodyBovine
GM-Tg-equg-IP2919-Ab-1/ GM-Tg-equg-IP2919-Ab-2Anti-Equine TSPYL5 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2919-Ab-1/ GM-Tg-hg-IP2919-Ab-2; GM-Tg-rg-IP2919-Ab-1/ GM-Tg-rg-IP2919-Ab-2;
GM-Tg-mg-IP2919-Ab-1/ GM-Tg-mg-IP2919-Ab-2; GM-Tg-cynog-IP2919-Ab-1/ GM-Tg-cynog-IP2919-Ab-2;
GM-Tg-felg-IP2919-Ab-1/ GM-Tg-felg-IP2919-Ab-2; GM-Tg-cang-IP2919-Ab-1/ GM-Tg-cang-IP2919-Ab-2;
GM-Tg-bovg-IP2919-Ab-1/ GM-Tg-bovg-IP2919-Ab-2; GM-Tg-equg-IP2919-Ab-1/ GM-Tg-equg-IP2919-Ab-2
Products NameAnti-TSPYL5 monoclonal antibody
Formatmab
Target NameTSPYL5
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-TSPYL5 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2919-Ag-1Recombinant multi-species TSYL5/ TSPYL5 protein


    Target information

    Target IDGM-IP2919
    Target NameTSPYL5
    Gene ID85453,239364,314555,702081,119866761,101094731,615997,100059820
    Gene Symbol and Synonyms6330530B20,E130308C19Rik,TSPYL5
    Uniprot AccessionQ86VY4
    Uniprot Entry NameTSYL5_HUMAN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseBreast Cancer
    Gene EnsemblENSG00000180543
    Target ClassificationN/A

    The target: TSPYL5, gene name: TSPYL5, also named as . Predicted to enable chromatin binding activity and histone binding activity. Involved in several processes, including cellular response to gamma radiation; positive regulation of protein kinase B signaling; and positive regulation of protein ubiquitination. Predicted to be active in chromatin and nucleus. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.