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Anti-TYW1B monoclonal antibody
Pre-made anti-TYW1B monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to TYW1B/TYW1B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP2920-Ab-1/ GM-Tg-hg-IP2920-Ab-2 | Anti-Human TYW1B monoclonal antibody | Human |
| GM-Tg-rg-IP2920-Ab-1/ GM-Tg-rg-IP2920-Ab-2 | Anti-Rat TYW1B monoclonal antibody | Rat |
| GM-Tg-mg-IP2920-Ab-1/ GM-Tg-mg-IP2920-Ab-2 | Anti-Mouse TYW1B monoclonal antibody | Mouse |
| GM-Tg-cynog-IP2920-Ab-1/ GM-Tg-cynog-IP2920-Ab-2 | Anti-Cynomolgus/ Rhesus macaque TYW1B monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP2920-Ab-1/ GM-Tg-felg-IP2920-Ab-2 | Anti-Feline TYW1B monoclonal antibody | Feline |
| GM-Tg-cang-IP2920-Ab-1/ GM-Tg-cang-IP2920-Ab-2 | Anti-Canine TYW1B monoclonal antibody | Canine |
| GM-Tg-bovg-IP2920-Ab-1/ GM-Tg-bovg-IP2920-Ab-2 | Anti-Bovine TYW1B monoclonal antibody | Bovine |
| GM-Tg-equg-IP2920-Ab-1/ GM-Tg-equg-IP2920-Ab-2 | Anti-Equine TYW1B monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP2920-Ab-1/ GM-Tg-hg-IP2920-Ab-2; GM-Tg-rg-IP2920-Ab-1/ GM-Tg-rg-IP2920-Ab-2; GM-Tg-mg-IP2920-Ab-1/ GM-Tg-mg-IP2920-Ab-2; GM-Tg-cynog-IP2920-Ab-1/ GM-Tg-cynog-IP2920-Ab-2; GM-Tg-felg-IP2920-Ab-1/ GM-Tg-felg-IP2920-Ab-2; GM-Tg-cang-IP2920-Ab-1/ GM-Tg-cang-IP2920-Ab-2; GM-Tg-bovg-IP2920-Ab-1/ GM-Tg-bovg-IP2920-Ab-2; GM-Tg-equg-IP2920-Ab-1/ GM-Tg-equg-IP2920-Ab-2 |
| Products Name | Anti-TYW1B monoclonal antibody |
| Format | mab |
| Target Name | TYW1B |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-TYW1B monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP2920-Ag-1 | Recombinant multi-species TYW1B/ LINC00069/ NCRNA00069 protein |
Target information
| Target ID | GM-IP2920 |
| Target Name | TYW1B |
| Gene ID | 441250 |
| Gene Symbol and Synonyms | LINC00069,NCRNA00069,RSAFD2,TYW1B |
| Uniprot Accession | Q6NUM6 |
| Uniprot Entry Name | TYW1B_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000277149 |
| Target Classification | N/A |
The target: TYW1B, gene name: TYW1B, also named as LINC00069, NCRNA00069, RSAFD2. Wybutosine is a hypermodified guanosine found in phenylalanine tRNA. Wybutosine functions to stabilize codon-anticodon interactions during ribosome decoding and therefore supports the maintenance of the reading frame. In yeast, the homolog of this gene is essential for the synthesis of wybutosine. The human genome contains two closely related genes that putatively function in wybutosine synthesis. The open reading frame of this locus is disrupted in some individuals. Thus, this locus appears to be an evolving pseudogene, but may still be functional in some members of the population. [provided by RefSeq, Apr 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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