Anti-ATRAP/ AGTRAP monoclonal antibody
Anti-ATRAP/ AGTRAP antibody for FACS & in-vivo assay
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-MP0048-Ab-1/ GM-Tg-hg-MP0048-Ab-2 | Anti-Human AGTRAP monoclonal antibody | Human |
GM-Tg-rg-MP0048-Ab-1/ GM-Tg-rg-MP0048-Ab-2 | Anti-Rat AGTRAP monoclonal antibody | Rat |
GM-Tg-mg-MP0048-Ab-1/ GM-Tg-mg-MP0048-Ab-2 | Anti-Mouse AGTRAP monoclonal antibody | Mouse |
GM-Tg-cynog-MP0048-Ab-1/ GM-Tg-cynog-MP0048-Ab-2 | Anti-Cynomolgus/ Rhesus macaque AGTRAP monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-MP0048-Ab-1/ GM-Tg-felg-MP0048-Ab-2 | Anti-Feline AGTRAP monoclonal antibody | Feline |
GM-Tg-cang-MP0048-Ab-1/ GM-Tg-cang-MP0048-Ab-2 | Anti-Canine AGTRAP monoclonal antibody | Canine |
GM-Tg-bovg-MP0048-Ab-1/ GM-Tg-bovg-MP0048-Ab-2 | Anti-Bovine AGTRAP monoclonal antibody | Bovine |
GM-Tg-equg-MP0048-Ab-1/ GM-Tg-equg-MP0048-Ab-2 | Anti-Equine AGTRAP monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-MP0048-Ab-1/ GM-Tg-hg-MP0048-Ab-2; GM-Tg-rg-MP0048-Ab-1/ GM-Tg-rg-MP0048-Ab-2; GM-Tg-mg-MP0048-Ab-1/ GM-Tg-mg-MP0048-Ab-2; GM-Tg-cynog-MP0048-Ab-1/ GM-Tg-cynog-MP0048-Ab-2; GM-Tg-felg-MP0048-Ab-1/ GM-Tg-felg-MP0048-Ab-2; GM-Tg-cang-MP0048-Ab-1/ GM-Tg-cang-MP0048-Ab-2; GM-Tg-bovg-MP0048-Ab-1/ GM-Tg-bovg-MP0048-Ab-2; GM-Tg-equg-MP0048-Ab-1/ GM-Tg-equg-MP0048-Ab-2 |
Products Name | Anti-AGTRAP monoclonal antibody |
Format | mab |
Target Name | AGTRAP |
Protein Sub-location | Transmembrane Protein |
Category of antibody | FACS/Biofunctional Antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-AGTRAP benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | Products Developing | Multi-species ATRAP/ AGTRAP VLP (virus-like particle) (Products Developing) |
ORF Viral Vector | vGMLP000862 | human AGTRAP Lentivirus particle |
ORF Viral Vector | pGMLP000862 | human AGTRAP Lentivirus plasmid |
ORF Viral Vector | vGMLP001187 | human AGTRAP Lentivirus particle |
ORF Viral Vector | pGMLP001187 | human AGTRAP Lentivirus plasmid |
ORF Viral Vector | pGMAD000025 | rat Agtrap Adenovirus plasmid |
ORF Viral Vector | pGMAAV000043 | mouse Agtrap AAV plasmid |
ORF Viral Vector | vGMAD000025 | rat Agtrap Adenovirus particle |
ORF Viral Vector | vGMAAV000043 | mouse Agtrap AAV particle |
Target information
Target ID | GM-MP0048 |
Target Name | AGTRAP |
Gene ID | 57085,11610,298646,722746,608333,102901287,508521,100051052 |
Gene Symbol and Synonyms | 3300002E14Rik,AGTRAP,AT1R,ATRAP,D4Wsu124e |
Uniprot Accession | Q6RW13,Q642A2 |
Uniprot Entry Name | ATRAP_HUMAN,ATRAP_RAT |
Protein Sub-location | Transmembrane Protein |
Category | |
Disease | N/A |
Gene Ensembl | ENSG00000177674 |
Target Classification | N/A |
The target: AGTRAP, gene name: AGTRAP, also named as ATRAP. This gene encodes a transmembrane protein localized to the plasma membrane and perinuclear vesicular structures. The gene product interacts with the angiotensin II type I receptor and negatively regulates angiotensin II signaling. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.