Anti-ATRAP/ AGTRAP monoclonal antibody

Anti-ATRAP/ AGTRAP antibody for FACS & in-vivo assay

Target products collectionGo to AGTRAP/AGTRAP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0048-Ab-1/ GM-Tg-hg-MP0048-Ab-2Anti-Human AGTRAP monoclonal antibodyHuman
GM-Tg-rg-MP0048-Ab-1/ GM-Tg-rg-MP0048-Ab-2Anti-Rat AGTRAP monoclonal antibodyRat
GM-Tg-mg-MP0048-Ab-1/ GM-Tg-mg-MP0048-Ab-2Anti-Mouse AGTRAP monoclonal antibodyMouse
GM-Tg-cynog-MP0048-Ab-1/ GM-Tg-cynog-MP0048-Ab-2Anti-Cynomolgus/ Rhesus macaque AGTRAP monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0048-Ab-1/ GM-Tg-felg-MP0048-Ab-2Anti-Feline AGTRAP monoclonal antibodyFeline
GM-Tg-cang-MP0048-Ab-1/ GM-Tg-cang-MP0048-Ab-2Anti-Canine AGTRAP monoclonal antibodyCanine
GM-Tg-bovg-MP0048-Ab-1/ GM-Tg-bovg-MP0048-Ab-2Anti-Bovine AGTRAP monoclonal antibodyBovine
GM-Tg-equg-MP0048-Ab-1/ GM-Tg-equg-MP0048-Ab-2Anti-Equine AGTRAP monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0048-Ab-1/ GM-Tg-hg-MP0048-Ab-2; GM-Tg-rg-MP0048-Ab-1/ GM-Tg-rg-MP0048-Ab-2;
GM-Tg-mg-MP0048-Ab-1/ GM-Tg-mg-MP0048-Ab-2; GM-Tg-cynog-MP0048-Ab-1/ GM-Tg-cynog-MP0048-Ab-2;
GM-Tg-felg-MP0048-Ab-1/ GM-Tg-felg-MP0048-Ab-2; GM-Tg-cang-MP0048-Ab-1/ GM-Tg-cang-MP0048-Ab-2;
GM-Tg-bovg-MP0048-Ab-1/ GM-Tg-bovg-MP0048-Ab-2; GM-Tg-equg-MP0048-Ab-1/ GM-Tg-equg-MP0048-Ab-2
Products NameAnti-AGTRAP monoclonal antibody
Formatmab
Target NameAGTRAP
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-AGTRAP benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species ATRAP/ AGTRAP VLP (virus-like particle) (Products Developing)
    ORF Viral VectorvGMLP000862human AGTRAP Lentivirus particle
    ORF Viral VectorpGMLP000862human AGTRAP Lentivirus plasmid
    ORF Viral VectorvGMLP001187human AGTRAP Lentivirus particle
    ORF Viral VectorpGMLP001187human AGTRAP Lentivirus plasmid
    ORF Viral VectorpGMAD000025rat Agtrap Adenovirus plasmid
    ORF Viral VectorpGMAAV000043mouse Agtrap AAV plasmid
    ORF Viral VectorvGMAD000025rat Agtrap Adenovirus particle
    ORF Viral VectorvGMAAV000043mouse Agtrap AAV particle


    Target information

    Target IDGM-MP0048
    Target NameAGTRAP
    Gene ID57085,11610,298646,722746,608333,102901287,508521,100051052
    Gene Symbol and Synonyms3300002E14Rik,AGTRAP,AT1R,ATRAP,D4Wsu124e
    Uniprot AccessionQ6RW13,Q642A2
    Uniprot Entry NameATRAP_HUMAN,ATRAP_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000177674
    Target ClassificationN/A

    The target: AGTRAP, gene name: AGTRAP, also named as ATRAP. This gene encodes a transmembrane protein localized to the plasma membrane and perinuclear vesicular structures. The gene product interacts with the angiotensin II type I receptor and negatively regulates angiotensin II signaling. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.