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Anti-AMBP/ A1M/ EDC1 monoclonal antibody
Anti-AMBP/ A1M/ EDC1 antibody for FACS & in-vivo assay
Go to AMBP/AMBP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP0055-Ab-1/ GM-Tg-hg-MP0055-Ab-2 | Anti-Human AMBP monoclonal antibody | Human |
| GM-Tg-rg-MP0055-Ab-1/ GM-Tg-rg-MP0055-Ab-2 | Anti-Rat AMBP monoclonal antibody | Rat |
| GM-Tg-mg-MP0055-Ab-1/ GM-Tg-mg-MP0055-Ab-2 | Anti-Mouse AMBP monoclonal antibody | Mouse |
| GM-Tg-cynog-MP0055-Ab-1/ GM-Tg-cynog-MP0055-Ab-2 | Anti-Cynomolgus/ Rhesus macaque AMBP monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP0055-Ab-1/ GM-Tg-felg-MP0055-Ab-2 | Anti-Feline AMBP monoclonal antibody | Feline |
| GM-Tg-cang-MP0055-Ab-1/ GM-Tg-cang-MP0055-Ab-2 | Anti-Canine AMBP monoclonal antibody | Canine |
| GM-Tg-bovg-MP0055-Ab-1/ GM-Tg-bovg-MP0055-Ab-2 | Anti-Bovine AMBP monoclonal antibody | Bovine |
| GM-Tg-equg-MP0055-Ab-1/ GM-Tg-equg-MP0055-Ab-2 | Anti-Equine AMBP monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP0055-Ab-1/ GM-Tg-hg-MP0055-Ab-2; GM-Tg-rg-MP0055-Ab-1/ GM-Tg-rg-MP0055-Ab-2; GM-Tg-mg-MP0055-Ab-1/ GM-Tg-mg-MP0055-Ab-2; GM-Tg-cynog-MP0055-Ab-1/ GM-Tg-cynog-MP0055-Ab-2; GM-Tg-felg-MP0055-Ab-1/ GM-Tg-felg-MP0055-Ab-2; GM-Tg-cang-MP0055-Ab-1/ GM-Tg-cang-MP0055-Ab-2; GM-Tg-bovg-MP0055-Ab-1/ GM-Tg-bovg-MP0055-Ab-2; GM-Tg-equg-MP0055-Ab-1/ GM-Tg-equg-MP0055-Ab-2 |
| Products Name | Anti-AMBP monoclonal antibody |
| Format | mab |
| Target Name | AMBP |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Diagnostic target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-AMBP benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species AMBP/ A1M/ EDC1 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLP000555 | human AMBP Lentivirus particle |
| ORF Viral Vector | pGMLP000555 | human AMBP Lentivirus plasmid |
| ORF Viral Vector | vGMAP000514 | Human AMBP Adenovirus particle |
| ORF Viral Vector | pGMAP000514 | Human AMBP Adenovirus plasmid |
| ORF Viral Vector | pGMLPm002841 | mouse Ambp Lentivirus plasmid |
| ORF Viral Vector | vGMLPm002841 | mouse Ambp Lentivirus particle |
Target information
| Target ID | GM-MP0055 |
| Target Name | AMBP |
| Gene ID | 259,11699,25377,704425,481685,100510797,280996,100051766 |
| Gene Symbol and Synonyms | A1M,AMBP,ASPI,EDC1,HCP,HI-30,HI30,IATIL,Intin4,ITI,ITIL,ITILC,UTI |
| Uniprot Accession | P02760,Q64240,P00978 |
| Uniprot Entry Name | AMBP_HUMAN,AMBP_RAT,AMBP_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | Diagnostics Biomarker |
| Disease | Ovary Cancer, Acute kidney failure, Complications of kidney transplant, Congenital occlusion of ureteropelvic junction, Contrast - Induced Nephropathy, Diabetic Nephropathy, IgA glomerulonephritis, Malignant neoplasm of bladder, Nephrotic syndrome with focal and segmental glomerular lesions, Other diseases of intestines (K55-K64), Type 1 diabetes mellitus, Type 2 diabetes mellitus, Type 2 diabetes mellitus with diabetic nephropathy, Balkan nephropathy |
| Gene Ensembl | ENSG00000106927 |
| Target Classification | N/A |
The target: AMBP, gene name: AMBP, also named as A1M, EDC1, HCP, HI30, IATIL, ITI, ITIL, ITILC, UTI. This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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