Anti-CD79A/ IGA/ MB-1 monoclonal antibody

Anti-CD79A/ IGA/ MB-1 antibody for FACS & in-vivo assay

Target products collectionGo to CD79A/CD79A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0216-Ab-1/ GM-Tg-hg-MP0216-Ab-2Anti-Human CD79A monoclonal antibodyHuman
GM-Tg-rg-MP0216-Ab-1/ GM-Tg-rg-MP0216-Ab-2Anti-Rat CD79A monoclonal antibodyRat
GM-Tg-mg-MP0216-Ab-1/ GM-Tg-mg-MP0216-Ab-2Anti-Mouse CD79A monoclonal antibodyMouse
GM-Tg-cynog-MP0216-Ab-1/ GM-Tg-cynog-MP0216-Ab-2Anti-Cynomolgus/ Rhesus macaque CD79A monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0216-Ab-1/ GM-Tg-felg-MP0216-Ab-2Anti-Feline CD79A monoclonal antibodyFeline
GM-Tg-cang-MP0216-Ab-1/ GM-Tg-cang-MP0216-Ab-2Anti-Canine CD79A monoclonal antibodyCanine
GM-Tg-bovg-MP0216-Ab-1/ GM-Tg-bovg-MP0216-Ab-2Anti-Bovine CD79A monoclonal antibodyBovine
GM-Tg-equg-MP0216-Ab-1/ GM-Tg-equg-MP0216-Ab-2Anti-Equine CD79A monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0216-Ab-1/ GM-Tg-hg-MP0216-Ab-2; GM-Tg-rg-MP0216-Ab-1/ GM-Tg-rg-MP0216-Ab-2;
GM-Tg-mg-MP0216-Ab-1/ GM-Tg-mg-MP0216-Ab-2; GM-Tg-cynog-MP0216-Ab-1/ GM-Tg-cynog-MP0216-Ab-2;
GM-Tg-felg-MP0216-Ab-1/ GM-Tg-felg-MP0216-Ab-2; GM-Tg-cang-MP0216-Ab-1/ GM-Tg-cang-MP0216-Ab-2;
GM-Tg-bovg-MP0216-Ab-1/ GM-Tg-bovg-MP0216-Ab-2; GM-Tg-equg-MP0216-Ab-1/ GM-Tg-equg-MP0216-Ab-2
Products NameAnti-CD79A monoclonal antibody
Formatmab
Target NameCD79A
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CD79A benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species CD79A/ IGA/ MB-1 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorvGMAP000491Human CD79A Adenovirus particle
    ORF Viral VectorpGMAP000491Human CD79A Adenovirus plasmid
    ORF Viral VectorpGMLPm001904mouse Cd79a Lentivirus plasmid
    ORF Viral VectorvGMLPm001904mouse Cd79a Lentivirus particle


    Target information

    Target IDGM-MP0216
    Target NameCD79A
    Gene ID973,12518,100913063,722190,484483,101083127,281674,100052219
    Gene Symbol and SynonymsCD79A,Cd79al,Ig-alpha,IGA,IGAlpha,Ly-54,Ly54,MB-1,MB1
    Uniprot AccessionP11912,P0CAN6,P40293
    Uniprot Entry NameCD79A_HUMAN,CD79A_CANLF,CD79A_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseCancer
    Gene EnsemblENSG00000105369
    Target ClassificationTumor-associated antigen (TAA)

    The target: CD79A, gene name: CD79A, also named as IGA, MB-1. The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.