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Anti-MUC2/ MLP/ MUC-2 monoclonal antibody
Anti-MUC2/ MLP/ MUC-2 antibody for FACS & in-vivo assay
Go to MUC2/MUC2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP2605-Ab-1/ GM-Tg-hg-MP2605-Ab-2 | Anti-Human MUC2 monoclonal antibody | Human |
| GM-Tg-rg-MP2605-Ab-1/ GM-Tg-rg-MP2605-Ab-2 | Anti-Rat MUC2 monoclonal antibody | Rat |
| GM-Tg-mg-MP2605-Ab-1/ GM-Tg-mg-MP2605-Ab-2 | Anti-Mouse MUC2 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP2605-Ab-1/ GM-Tg-cynog-MP2605-Ab-2 | Anti-Cynomolgus/ Rhesus macaque MUC2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP2605-Ab-1/ GM-Tg-felg-MP2605-Ab-2 | Anti-Feline MUC2 monoclonal antibody | Feline |
| GM-Tg-cang-MP2605-Ab-1/ GM-Tg-cang-MP2605-Ab-2 | Anti-Canine MUC2 monoclonal antibody | Canine |
| GM-Tg-bovg-MP2605-Ab-1/ GM-Tg-bovg-MP2605-Ab-2 | Anti-Bovine MUC2 monoclonal antibody | Bovine |
| GM-Tg-equg-MP2605-Ab-1/ GM-Tg-equg-MP2605-Ab-2 | Anti-Equine MUC2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP2605-Ab-1/ GM-Tg-hg-MP2605-Ab-2; GM-Tg-rg-MP2605-Ab-1/ GM-Tg-rg-MP2605-Ab-2; GM-Tg-mg-MP2605-Ab-1/ GM-Tg-mg-MP2605-Ab-2; GM-Tg-cynog-MP2605-Ab-1/ GM-Tg-cynog-MP2605-Ab-2; GM-Tg-felg-MP2605-Ab-1/ GM-Tg-felg-MP2605-Ab-2; GM-Tg-cang-MP2605-Ab-1/ GM-Tg-cang-MP2605-Ab-2; GM-Tg-bovg-MP2605-Ab-1/ GM-Tg-bovg-MP2605-Ab-2; GM-Tg-equg-MP2605-Ab-1/ GM-Tg-equg-MP2605-Ab-2 |
| Products Name | Anti-MUC2 monoclonal antibody |
| Format | mab |
| Target Name | MUC2 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-MUC2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species MUC2/ MLP/ MUC-2 VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-MP2605 |
| Target Name | MUC2 |
| Gene ID | 4583,17831,24572,720903,119864303,101096605,789571 |
| Gene Symbol and Synonyms | 2010015E03Rik,AABR07006030.1,HH-Muc,MCM,MLP,MUC-2,MUC2,mucin-2,SMUC,wnn |
| Uniprot Accession | Q02817,P98089,Q62635 |
| Uniprot Entry Name | MUC2_HUMAN,MUC2L_RAT,MUC2_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | Cancer |
| Gene Ensembl | ENSG00000198788 |
| Target Classification | Tumor-associated antigen (TAA) |
The target: MUC2, gene name: MUC2, also named as MLP, MUC-2, SMUC. This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The protein polymerizes into a gel of which 80% is composed of oligosaccharide side chains by weight. The protein features a central domain containing tandem repeats rich in threonine and proline that varies between 50 and 115 copies in different individuals. Downregulation of this gene has been observed in patients with Crohn disease and ulcerative colitis. [provided by RefSeq, Oct 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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