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Anti-CHSTB/ CHST11/ C4ST functional antibody
Anti-CHSTB/ CHST11/ C4ST functional antibody for cell culture, ELISA & in-vivo assay
Go to CHST11/CHST11 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0084-Ab-1/ GM-Tg-hg-SE0084-Ab-2 | Anti-Human CHST11 monoclonal antibody | Human |
| GM-Tg-rg-SE0084-Ab-1/ GM-Tg-rg-SE0084-Ab-2 | Anti-Rat CHST11 monoclonal antibody | Rat |
| GM-Tg-mg-SE0084-Ab-1/ GM-Tg-mg-SE0084-Ab-2 | Anti-Mouse CHST11 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0084-Ab-1/ GM-Tg-cynog-SE0084-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CHST11 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0084-Ab-1/ GM-Tg-felg-SE0084-Ab-2 | Anti-Feline CHST11 monoclonal antibody | Feline |
| GM-Tg-cang-SE0084-Ab-1/ GM-Tg-cang-SE0084-Ab-2 | Anti-Canine CHST11 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0084-Ab-1/ GM-Tg-bovg-SE0084-Ab-2 | Anti-Bovine CHST11 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0084-Ab-1/ GM-Tg-equg-SE0084-Ab-2 | Anti-Equine CHST11 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0084-Ab-1/ GM-Tg-hg-SE0084-Ab-2; GM-Tg-rg-SE0084-Ab-1/ GM-Tg-rg-SE0084-Ab-2; GM-Tg-mg-SE0084-Ab-1/ GM-Tg-mg-SE0084-Ab-2; GM-Tg-cynog-SE0084-Ab-1/ GM-Tg-cynog-SE0084-Ab-2; GM-Tg-felg-SE0084-Ab-1/ GM-Tg-felg-SE0084-Ab-2; GM-Tg-cang-SE0084-Ab-1/ GM-Tg-cang-SE0084-Ab-2; GM-Tg-bovg-SE0084-Ab-1/ GM-Tg-bovg-SE0084-Ab-2; GM-Tg-equg-SE0084-Ab-1/ GM-Tg-equg-SE0084-Ab-2 |
| Products Name | Anti-CHST11 monoclonal antibody |
| Format | mab |
| Target Name | CHST11 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CHST11 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0084-Ag-1 | Recombinant multi-species CHSTB/ CHST11/ C4ST protein |
Target information
| Target ID | GM-SE0084 |
| Target Name | CHST11 |
| Gene ID | 50515,58250,314694,700690,481299,101085731,528860,100067989 |
| Gene Symbol and Synonyms | 1110020P09Rik,C4s,C4ST,C4ST-1,C4ST1,CHST11,HSA269537,OCBMD |
| Uniprot Accession | Q9NPF2,P69478 |
| Uniprot Entry Name | CHSTB_HUMAN,CHSTB_RAT |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000171310 |
| Target Classification | N/A |
The target: CHST11, gene name: CHST11, also named as C4ST, C4ST-1, C4ST1, HSA269537. The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. A chromosomal translocation involving this gene and IgH, t(12;14)(q23;q32), has been reported in a patient with B-cell chronic lymphocytic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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