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Anti-CHST8/ GALNAC4ST1/ GalNAc4ST functional antibody
Anti-CHST8/ GALNAC4ST1/ GalNAc4ST functional antibody for cell culture, ELISA & in-vivo assay
Go to CHST8/CHST8 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0088-Ab-1/ GM-Tg-hg-SE0088-Ab-2 | Anti-Human CHST8 monoclonal antibody | Human |
| GM-Tg-rg-SE0088-Ab-1/ GM-Tg-rg-SE0088-Ab-2 | Anti-Rat CHST8 monoclonal antibody | Rat |
| GM-Tg-mg-SE0088-Ab-1/ GM-Tg-mg-SE0088-Ab-2 | Anti-Mouse CHST8 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0088-Ab-1/ GM-Tg-cynog-SE0088-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CHST8 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0088-Ab-1/ GM-Tg-felg-SE0088-Ab-2 | Anti-Feline CHST8 monoclonal antibody | Feline |
| GM-Tg-cang-SE0088-Ab-1/ GM-Tg-cang-SE0088-Ab-2 | Anti-Canine CHST8 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0088-Ab-1/ GM-Tg-bovg-SE0088-Ab-2 | Anti-Bovine CHST8 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0088-Ab-1/ GM-Tg-equg-SE0088-Ab-2 | Anti-Equine CHST8 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0088-Ab-1/ GM-Tg-hg-SE0088-Ab-2; GM-Tg-rg-SE0088-Ab-1/ GM-Tg-rg-SE0088-Ab-2; GM-Tg-mg-SE0088-Ab-1/ GM-Tg-mg-SE0088-Ab-2; GM-Tg-cynog-SE0088-Ab-1/ GM-Tg-cynog-SE0088-Ab-2; GM-Tg-felg-SE0088-Ab-1/ GM-Tg-felg-SE0088-Ab-2; GM-Tg-cang-SE0088-Ab-1/ GM-Tg-cang-SE0088-Ab-2; GM-Tg-bovg-SE0088-Ab-1/ GM-Tg-bovg-SE0088-Ab-2; GM-Tg-equg-SE0088-Ab-1/ GM-Tg-equg-SE0088-Ab-2 |
| Products Name | Anti-CHST8 monoclonal antibody |
| Format | mab |
| Target Name | CHST8 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CHST8 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0088-Ag-1 | Recombinant multi-species CHST8/ GALNAC4ST1/ GalNAc4ST protein |
Target information
| Target ID | GM-SE0088 |
| Target Name | CHST8 |
| Gene ID | 64377,68947,308511,106992411,484596,101090569,100271926,100050006 |
| Gene Symbol and Synonyms | 1500011J21Rik,CHST8,GalNAc4ST,GALNAC4ST1,PSS3 |
| Uniprot Accession | Q9H2A9 |
| Uniprot Entry Name | CHST8_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000124302 |
| Target Classification | N/A |
The target: CHST8, gene name: CHST8, also named as GALNAC4ST1, GalNAc4ST, PSS3. The protein encoded by this gene belongs to the sulfotransferase 2 family. It is predominantly expressed in the pituitary gland, and is localized to the golgi membrane. This protein catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. It is responsible for sulfation of GalNAc on luteinizing hormone (LH), which is required for production of the sex hormones. Mice lacking this enzyme, exhibit increased levels of circulating LH, and precocious sexual maturation of both male and female mice. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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