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Anti-CO6A2/ COL6A2/ BTHLM1 functional antibody
Anti-CO6A2/ COL6A2/ BTHLM1 functional antibody for cell culture, ELISA & in-vivo assay
Go to COL6A2/COL6A2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0112-Ab-1/ GM-Tg-hg-SE0112-Ab-2 | Anti-Human COL6A2 monoclonal antibody | Human |
| GM-Tg-rg-SE0112-Ab-1/ GM-Tg-rg-SE0112-Ab-2 | Anti-Rat COL6A2 monoclonal antibody | Rat |
| GM-Tg-mg-SE0112-Ab-1/ GM-Tg-mg-SE0112-Ab-2 | Anti-Mouse COL6A2 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0112-Ab-1/ GM-Tg-cynog-SE0112-Ab-2 | Anti-Cynomolgus/ Rhesus macaque COL6A2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0112-Ab-1/ GM-Tg-felg-SE0112-Ab-2 | Anti-Feline COL6A2 monoclonal antibody | Feline |
| GM-Tg-cang-SE0112-Ab-1/ GM-Tg-cang-SE0112-Ab-2 | Anti-Canine COL6A2 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0112-Ab-1/ GM-Tg-bovg-SE0112-Ab-2 | Anti-Bovine COL6A2 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0112-Ab-1/ GM-Tg-equg-SE0112-Ab-2 | Anti-Equine COL6A2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0112-Ab-1/ GM-Tg-hg-SE0112-Ab-2; GM-Tg-rg-SE0112-Ab-1/ GM-Tg-rg-SE0112-Ab-2; GM-Tg-mg-SE0112-Ab-1/ GM-Tg-mg-SE0112-Ab-2; GM-Tg-cynog-SE0112-Ab-1/ GM-Tg-cynog-SE0112-Ab-2; GM-Tg-felg-SE0112-Ab-1/ GM-Tg-felg-SE0112-Ab-2; GM-Tg-cang-SE0112-Ab-1/ GM-Tg-cang-SE0112-Ab-2; GM-Tg-bovg-SE0112-Ab-1/ GM-Tg-bovg-SE0112-Ab-2; GM-Tg-equg-SE0112-Ab-1/ GM-Tg-equg-SE0112-Ab-2 |
| Products Name | Anti-COL6A2 monoclonal antibody |
| Format | mab |
| Target Name | COL6A2 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-COL6A2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0112-Ag-1 | Recombinant multi-species CO6A2/ COL6A2/ BTHLM1 protein |
| ORF Viral Vector | pGMLP001476 | human COL6A2 Lentivirus plasmid |
| ORF Viral Vector | vGMLP001476 | human COL6A2 Lentivirus particle |
Target information
| Target ID | GM-SE0112 |
| Target Name | COL6A2 |
| Gene ID | 1292,12834,361821,709493,100856491,101100658,282194,100055332 |
| Gene Symbol and Synonyms | BTHLM1,Col6a-2,COL6A2,PP3610,UCMD1 |
| Uniprot Accession | P12110 |
| Uniprot Entry Name | CO6A2_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000142173 |
| Target Classification | N/A |
The target: COL6A2, gene name: COL6A2, also named as BTHLM1, PP3610, UCMD1. This gene encodes one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. The product of this gene contains several domains similar to von Willebrand Factor type A domains. These domains have been shown to bind extracellular matrix proteins, an interaction that explains the importance of this collagen in organizing matrix components. Mutations in this gene are associated with Bethlem myopathy and Ullrich scleroatonic muscular dystrophy. Three transcript variants have been identified for this gene. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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