Anti-GT251/ COLGALT1/ ColGalT 1 functional antibody

Anti-GT251/ COLGALT1/ ColGalT 1 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to COLGALT1/COLGALT1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0115-Ab-1/ GM-Tg-hg-SE0115-Ab-2Anti-Human COLGALT1 monoclonal antibodyHuman
GM-Tg-rg-SE0115-Ab-1/ GM-Tg-rg-SE0115-Ab-2Anti-Rat COLGALT1 monoclonal antibodyRat
GM-Tg-mg-SE0115-Ab-1/ GM-Tg-mg-SE0115-Ab-2Anti-Mouse COLGALT1 monoclonal antibodyMouse
GM-Tg-cynog-SE0115-Ab-1/ GM-Tg-cynog-SE0115-Ab-2Anti-Cynomolgus/ Rhesus macaque COLGALT1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0115-Ab-1/ GM-Tg-felg-SE0115-Ab-2Anti-Feline COLGALT1 monoclonal antibodyFeline
GM-Tg-cang-SE0115-Ab-1/ GM-Tg-cang-SE0115-Ab-2Anti-Canine COLGALT1 monoclonal antibodyCanine
GM-Tg-bovg-SE0115-Ab-1/ GM-Tg-bovg-SE0115-Ab-2Anti-Bovine COLGALT1 monoclonal antibodyBovine
GM-Tg-equg-SE0115-Ab-1/ GM-Tg-equg-SE0115-Ab-2Anti-Equine COLGALT1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0115-Ab-1/ GM-Tg-hg-SE0115-Ab-2; GM-Tg-rg-SE0115-Ab-1/ GM-Tg-rg-SE0115-Ab-2;
GM-Tg-mg-SE0115-Ab-1/ GM-Tg-mg-SE0115-Ab-2; GM-Tg-cynog-SE0115-Ab-1/ GM-Tg-cynog-SE0115-Ab-2;
GM-Tg-felg-SE0115-Ab-1/ GM-Tg-felg-SE0115-Ab-2; GM-Tg-cang-SE0115-Ab-1/ GM-Tg-cang-SE0115-Ab-2;
GM-Tg-bovg-SE0115-Ab-1/ GM-Tg-bovg-SE0115-Ab-2; GM-Tg-equg-SE0115-Ab-1/ GM-Tg-equg-SE0115-Ab-2
Products NameAnti-COLGALT1 monoclonal antibody
Formatmab
Target NameCOLGALT1
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-COLGALT1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0115-Ag-1Recombinant multi-species GT251/ COLGALT1/ ColGalT 1 protein


    Target information

    Target IDGM-SE0115
    Target NameCOLGALT1
    Gene ID79709,234407,290637,719980,484834,101091350,513167,100070236
    Gene Symbol and Synonyms2810024B22Rik,BSVD3,ColGalT 1,COLGALT1,GLT25D1,RGD1309002
    Uniprot AccessionQ8NBJ5,A5PK45
    Uniprot Entry NameGT251_HUMAN,GT251_BOVIN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000130309
    Target ClassificationN/A

    The target: COLGALT1, gene name: COLGALT1, also named as ColGalT 1, GLT25D1. The protein encoded by this gene is one of two enzymes that transfers galactose moieties to hydroxylysine residues of collagen and mannose binding lectin. This gene is constitutively expressed and encodes a soluble protein that localizes to the endoplasmic reticulum. [provided by RefSeq, Dec 2015].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.