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Anti-CP2R1/ CYP2R1 functional antibody
Anti-CP2R1/ CYP2R1 functional antibody for cell culture, ELISA & in-vivo assay
Go to CYP2R1/CYP2R1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0142-Ab-1/ GM-Tg-hg-SE0142-Ab-2 | Anti-Human CYP2R1 monoclonal antibody | Human |
| GM-Tg-rg-SE0142-Ab-1/ GM-Tg-rg-SE0142-Ab-2 | Anti-Rat CYP2R1 monoclonal antibody | Rat |
| GM-Tg-mg-SE0142-Ab-1/ GM-Tg-mg-SE0142-Ab-2 | Anti-Mouse CYP2R1 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0142-Ab-1/ GM-Tg-cynog-SE0142-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CYP2R1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0142-Ab-1/ GM-Tg-felg-SE0142-Ab-2 | Anti-Feline CYP2R1 monoclonal antibody | Feline |
| GM-Tg-cang-SE0142-Ab-1/ GM-Tg-cang-SE0142-Ab-2 | Anti-Canine CYP2R1 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0142-Ab-1/ GM-Tg-bovg-SE0142-Ab-2 | Anti-Bovine CYP2R1 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0142-Ab-1/ GM-Tg-equg-SE0142-Ab-2 | Anti-Equine CYP2R1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0142-Ab-1/ GM-Tg-hg-SE0142-Ab-2; GM-Tg-rg-SE0142-Ab-1/ GM-Tg-rg-SE0142-Ab-2; GM-Tg-mg-SE0142-Ab-1/ GM-Tg-mg-SE0142-Ab-2; GM-Tg-cynog-SE0142-Ab-1/ GM-Tg-cynog-SE0142-Ab-2; GM-Tg-felg-SE0142-Ab-1/ GM-Tg-felg-SE0142-Ab-2; GM-Tg-cang-SE0142-Ab-1/ GM-Tg-cang-SE0142-Ab-2; GM-Tg-bovg-SE0142-Ab-1/ GM-Tg-bovg-SE0142-Ab-2; GM-Tg-equg-SE0142-Ab-1/ GM-Tg-equg-SE0142-Ab-2 |
| Products Name | Anti-CYP2R1 monoclonal antibody |
| Format | mab |
| Target Name | CYP2R1 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CYP2R1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0142-Ag-1 | Recombinant multi-species CP2R1/ CYP2R1 protein |
| ORF Viral Vector | vGMLP001483 | human CYP2R1 Lentivirus particle |
| ORF Viral Vector | pGMLP001483 | human CYP2R1 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm002680 | mouse Cyp2r1 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm002681 | mouse Cyp2r1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm002680 | mouse Cyp2r1 Lentivirus particle |
| ORF Viral Vector | vGMLPm002681 | mouse Cyp2r1 Lentivirus particle |
Target information
| Target ID | GM-SE0142 |
| Target Name | CYP2R1 |
| Gene ID | 120227,244209,361631,698834,119865014,101093889,541302,100146381 |
| Gene Symbol and Synonyms | CYP2R1,LOC119865014 |
| Uniprot Accession | Q6VVX0 |
| Uniprot Entry Name | CP2R1_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000186104 |
| Target Classification | N/A |
The target: CYP2R1, gene name: CYP2R1, also named as . This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in this gene has been associated with selective 25-hydroxyvitamin D deficiency. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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