Anti-DRS7C/ DHRS7C/ SDR32C2 functional antibody

Anti-DRS7C/ DHRS7C/ SDR32C2 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to DHRS7C/DHRS7C products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0155-Ab-1/ GM-Tg-hg-SE0155-Ab-2Anti-Human DHRS7C monoclonal antibodyHuman
GM-Tg-rg-SE0155-Ab-1/ GM-Tg-rg-SE0155-Ab-2Anti-Rat DHRS7C monoclonal antibodyRat
GM-Tg-mg-SE0155-Ab-1/ GM-Tg-mg-SE0155-Ab-2Anti-Mouse DHRS7C monoclonal antibodyMouse
GM-Tg-cynog-SE0155-Ab-1/ GM-Tg-cynog-SE0155-Ab-2Anti-Cynomolgus/ Rhesus macaque DHRS7C monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0155-Ab-1/ GM-Tg-felg-SE0155-Ab-2Anti-Feline DHRS7C monoclonal antibodyFeline
GM-Tg-cang-SE0155-Ab-1/ GM-Tg-cang-SE0155-Ab-2Anti-Canine DHRS7C monoclonal antibodyCanine
GM-Tg-bovg-SE0155-Ab-1/ GM-Tg-bovg-SE0155-Ab-2Anti-Bovine DHRS7C monoclonal antibodyBovine
GM-Tg-equg-SE0155-Ab-1/ GM-Tg-equg-SE0155-Ab-2Anti-Equine DHRS7C monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0155-Ab-1/ GM-Tg-hg-SE0155-Ab-2; GM-Tg-rg-SE0155-Ab-1/ GM-Tg-rg-SE0155-Ab-2;
GM-Tg-mg-SE0155-Ab-1/ GM-Tg-mg-SE0155-Ab-2; GM-Tg-cynog-SE0155-Ab-1/ GM-Tg-cynog-SE0155-Ab-2;
GM-Tg-felg-SE0155-Ab-1/ GM-Tg-felg-SE0155-Ab-2; GM-Tg-cang-SE0155-Ab-1/ GM-Tg-cang-SE0155-Ab-2;
GM-Tg-bovg-SE0155-Ab-1/ GM-Tg-bovg-SE0155-Ab-2; GM-Tg-equg-SE0155-Ab-1/ GM-Tg-equg-SE0155-Ab-2
Products NameAnti-DHRS7C monoclonal antibody
Formatmab
Target NameDHRS7C
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-DHRS7C benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0155-Ag-1Recombinant multi-species DRS7C/ DHRS7C/ SDR32C2 protein


    Target information

    Target IDGM-SE0155
    Target NameDHRS7C
    Gene ID201140,68460,287411,722045,479501,101084145,511943,100073077
    Gene Symbol and Synonyms1110001P11Rik,DHRS7C,RGD1306989,SDR32C2,SRP-35
    Uniprot AccessionA6NNS2,D3ZGP9,Q1RMJ5
    Uniprot Entry NameDRS7C_HUMAN,DRS7C_RAT,DRS7C_BOVIN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000184544
    Target ClassificationN/A

    The target: DHRS7C, gene name: DHRS7C, also named as SDR32C2. Predicted to enable NAD-retinol dehydrogenase activity. Predicted to be involved in regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum. Predicted to be located in extracellular region and longitudinal sarcoplasmic reticulum. Predicted to be active in sarcoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.