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Anti-FBLN3/ EFEMP1/ DHRD functional antibody
Anti-FBLN3/ EFEMP1/ DHRD functional antibody for cell culture, ELISA & in-vivo assay
Go to EFEMP1/EFEMP1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0168-Ab-1/ GM-Tg-hg-SE0168-Ab-2 | Anti-Human EFEMP1 monoclonal antibody | Human |
| GM-Tg-rg-SE0168-Ab-1/ GM-Tg-rg-SE0168-Ab-2 | Anti-Rat EFEMP1 monoclonal antibody | Rat |
| GM-Tg-mg-SE0168-Ab-1/ GM-Tg-mg-SE0168-Ab-2 | Anti-Mouse EFEMP1 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0168-Ab-1/ GM-Tg-cynog-SE0168-Ab-2 | Anti-Cynomolgus/ Rhesus macaque EFEMP1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0168-Ab-1/ GM-Tg-felg-SE0168-Ab-2 | Anti-Feline EFEMP1 monoclonal antibody | Feline |
| GM-Tg-cang-SE0168-Ab-1/ GM-Tg-cang-SE0168-Ab-2 | Anti-Canine EFEMP1 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0168-Ab-1/ GM-Tg-bovg-SE0168-Ab-2 | Anti-Bovine EFEMP1 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0168-Ab-1/ GM-Tg-equg-SE0168-Ab-2 | Anti-Equine EFEMP1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0168-Ab-1/ GM-Tg-hg-SE0168-Ab-2; GM-Tg-rg-SE0168-Ab-1/ GM-Tg-rg-SE0168-Ab-2; GM-Tg-mg-SE0168-Ab-1/ GM-Tg-mg-SE0168-Ab-2; GM-Tg-cynog-SE0168-Ab-1/ GM-Tg-cynog-SE0168-Ab-2; GM-Tg-felg-SE0168-Ab-1/ GM-Tg-felg-SE0168-Ab-2; GM-Tg-cang-SE0168-Ab-1/ GM-Tg-cang-SE0168-Ab-2; GM-Tg-bovg-SE0168-Ab-1/ GM-Tg-bovg-SE0168-Ab-2; GM-Tg-equg-SE0168-Ab-1/ GM-Tg-equg-SE0168-Ab-2 |
| Products Name | Anti-EFEMP1 monoclonal antibody |
| Format | mab |
| Target Name | EFEMP1 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-EFEMP1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0168-Ag-1 | Recombinant multi-species FBLN3/ EFEMP1/ DHRD protein |
| ORF Viral Vector | pGMLP002671 | human EFEMP1 Lentivirus plasmid |
| ORF Viral Vector | vGMLP002671 | human EFEMP1 Lentivirus particle |
| ORF Viral Vector | pGMLPm001084 | mouse Efemp1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001084 | mouse Efemp1 Lentivirus particle |
Target information
| Target ID | GM-SE0168 |
| Target Name | EFEMP1 |
| Gene ID | 2202,216616,305604,718984,474604,101094585,511566,100066175 |
| Gene Symbol and Synonyms | DHRD,DRAD,EFEMP1,FBLN3,FBNL,FIBL-3,MLVT,MTLV,S1-5,T16 |
| Uniprot Accession | Q12805,O35568 |
| Uniprot Entry Name | FBLN3_HUMAN,FBLN3_RAT |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | Osteoarthritis |
| Gene Ensembl | ENSG00000115380 |
| Target Classification | N/A |
The target: EFEMP1, gene name: EFEMP1, also named as DHRD, DRAD, FBLN3, FBNL, FIBL-3, MLVT, MTLV, S1-5. This gene encodes a member of the fibulin family of extracellular matrix glycoproteins. Like all members of this family, the encoded protein contains tandemly repeated epidermal growth factor-like repeats followed by a C-terminus fibulin-type domain. This gene is upregulated in malignant gliomas and may play a role in the aggressive nature of these tumors. Mutations in this gene are associated with Doyne honeycomb retinal dystrophy. Alternatively spliced transcript variants that encode the same protein have been described.[provided by RefSeq, Nov 2009].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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