Anti-ENTP5/ ENTPD5/ CD39L4 functional antibody

Anti-ENTP5/ ENTPD5/ CD39L4 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to ENTPD5/ENTPD5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0178-Ab-1/ GM-Tg-hg-SE0178-Ab-2Anti-Human ENTPD5 monoclonal antibodyHuman
GM-Tg-rg-SE0178-Ab-1/ GM-Tg-rg-SE0178-Ab-2Anti-Rat ENTPD5 monoclonal antibodyRat
GM-Tg-mg-SE0178-Ab-1/ GM-Tg-mg-SE0178-Ab-2Anti-Mouse ENTPD5 monoclonal antibodyMouse
GM-Tg-cynog-SE0178-Ab-1/ GM-Tg-cynog-SE0178-Ab-2Anti-Cynomolgus/ Rhesus macaque ENTPD5 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0178-Ab-1/ GM-Tg-felg-SE0178-Ab-2Anti-Feline ENTPD5 monoclonal antibodyFeline
GM-Tg-cang-SE0178-Ab-1/ GM-Tg-cang-SE0178-Ab-2Anti-Canine ENTPD5 monoclonal antibodyCanine
GM-Tg-bovg-SE0178-Ab-1/ GM-Tg-bovg-SE0178-Ab-2Anti-Bovine ENTPD5 monoclonal antibodyBovine
GM-Tg-equg-SE0178-Ab-1/ GM-Tg-equg-SE0178-Ab-2Anti-Equine ENTPD5 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0178-Ab-1/ GM-Tg-hg-SE0178-Ab-2; GM-Tg-rg-SE0178-Ab-1/ GM-Tg-rg-SE0178-Ab-2;
GM-Tg-mg-SE0178-Ab-1/ GM-Tg-mg-SE0178-Ab-2; GM-Tg-cynog-SE0178-Ab-1/ GM-Tg-cynog-SE0178-Ab-2;
GM-Tg-felg-SE0178-Ab-1/ GM-Tg-felg-SE0178-Ab-2; GM-Tg-cang-SE0178-Ab-1/ GM-Tg-cang-SE0178-Ab-2;
GM-Tg-bovg-SE0178-Ab-1/ GM-Tg-bovg-SE0178-Ab-2; GM-Tg-equg-SE0178-Ab-1/ GM-Tg-equg-SE0178-Ab-2
Products NameAnti-ENTPD5 monoclonal antibody
Formatmab
Target NameENTPD5
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-ENTPD5 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0178-Ag-1Recombinant multi-species ENTP5/ ENTPD5/ CD39L4 protein
    ORF Viral VectorvGMLP004119human ENTPD5 Lentivirus particle
    ORF Viral VectorpGMLP004119human ENTPD5 Lentivirus plasmid
    ORF Viral VectorpGMLPm003818mouse Entpd5 Lentivirus plasmid
    ORF Viral VectorvGMLPm003818mouse Entpd5 Lentivirus particle


    Target information

    Target IDGM-SE0178
    Target NameENTPD5
    Gene ID957,12499,314312,698503,480384,101090270,533096,100056466
    Gene Symbol and SynonymsCD39L4,ENTPD5,ER-UDPase,mNTPase,NTPDase-5,NTPDase5,PCPH
    Uniprot AccessionO75356,Q6P6S9,E1BPW0
    Uniprot Entry NameENTP5_HUMAN,ENTP5_RAT,ENTP5_BOVIN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseProstate Cancer
    Gene EnsemblENSG00000187097
    Target ClassificationN/A

    The target: ENTPD5, gene name: ENTPD5, also named as CD39L4, NTPDase-5, PCPH. The protein encoded by this gene is similar to E-type nucleotidases (NTPases)/ecto-ATPase/apyrases. NTPases, such as CD39, mediate catabolism of extracellular nucleotides. ENTPD5 contains 4 apyrase-conserved regions which is characteristic of NTPases. [provided by RefSeq, Jan 2009].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.