Anti-FAF2/ ETEA/ UBXD8 functional antibody

Anti-FAF2/ ETEA/ UBXD8 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to FAF2/FAF2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0192-Ab-1/ GM-Tg-hg-SE0192-Ab-2Anti-Human FAF2 monoclonal antibodyHuman
GM-Tg-rg-SE0192-Ab-1/ GM-Tg-rg-SE0192-Ab-2Anti-Rat FAF2 monoclonal antibodyRat
GM-Tg-mg-SE0192-Ab-1/ GM-Tg-mg-SE0192-Ab-2Anti-Mouse FAF2 monoclonal antibodyMouse
GM-Tg-cynog-SE0192-Ab-1/ GM-Tg-cynog-SE0192-Ab-2Anti-Cynomolgus/ Rhesus macaque FAF2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0192-Ab-1/ GM-Tg-felg-SE0192-Ab-2Anti-Feline FAF2 monoclonal antibodyFeline
GM-Tg-cang-SE0192-Ab-1/ GM-Tg-cang-SE0192-Ab-2Anti-Canine FAF2 monoclonal antibodyCanine
GM-Tg-bovg-SE0192-Ab-1/ GM-Tg-bovg-SE0192-Ab-2Anti-Bovine FAF2 monoclonal antibodyBovine
GM-Tg-equg-SE0192-Ab-1/ GM-Tg-equg-SE0192-Ab-2Anti-Equine FAF2 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0192-Ab-1/ GM-Tg-hg-SE0192-Ab-2; GM-Tg-rg-SE0192-Ab-1/ GM-Tg-rg-SE0192-Ab-2;
GM-Tg-mg-SE0192-Ab-1/ GM-Tg-mg-SE0192-Ab-2; GM-Tg-cynog-SE0192-Ab-1/ GM-Tg-cynog-SE0192-Ab-2;
GM-Tg-felg-SE0192-Ab-1/ GM-Tg-felg-SE0192-Ab-2; GM-Tg-cang-SE0192-Ab-1/ GM-Tg-cang-SE0192-Ab-2;
GM-Tg-bovg-SE0192-Ab-1/ GM-Tg-bovg-SE0192-Ab-2; GM-Tg-equg-SE0192-Ab-1/ GM-Tg-equg-SE0192-Ab-2
Products NameAnti-FAF2 monoclonal antibody
Formatmab
Target NameFAF2
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-FAF2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0192-Ag-1Recombinant multi-species FAF2/ ETEA/ UBXD8 protein
    ORF Viral VectorvGMLP002597human FAF2 Lentivirus particle
    ORF Viral VectorpGMLP002597human FAF2 Lentivirus plasmid
    ORF Viral VectorpGMLPm004898mouse Faf2 Lentivirus plasmid
    ORF Viral VectorvGMLPm004898mouse Faf2 Lentivirus particle


    Target information

    Target IDGM-SE0192
    Target NameFAF2
    Gene ID23197,76577,291000,702555,489102,101081952,767948,100068860
    Gene Symbol and Synonyms2210404D11Rik,ETEA,FAF2,mKIAA0887,RGD1306577,UBX8,UBXD8,UBXN3B
    Uniprot AccessionQ96CS3,Q5BK32,Q2HJD0
    Uniprot Entry NameFAF2_HUMAN,FAF2_RAT,FAF2_BOVIN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000113194
    Target ClassificationN/A

    The target: FAF2, gene name: FAF2, also named as ETEA, UBXD8, UBXN3B. The protein encoded by this gene is highly expressed in peripheral blood of patients with atopic dermatitis (AD), compared to normal individuals. It may play a role in regulating the resistance to apoptosis that is observed in T cells and eosinophils of AD patients. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.