Anti-FDSCP/ FDCSP/ C4orf7 functional antibody

Anti-FDSCP/ FDCSP/ C4orf7 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to FDCSP/FDCSP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0214-Ab-1/ GM-Tg-hg-SE0214-Ab-2Anti-Human FDCSP monoclonal antibodyHuman
GM-Tg-rg-SE0214-Ab-1/ GM-Tg-rg-SE0214-Ab-2Anti-Rat FDCSP monoclonal antibodyRat
GM-Tg-mg-SE0214-Ab-1/ GM-Tg-mg-SE0214-Ab-2Anti-Mouse FDCSP monoclonal antibodyMouse
GM-Tg-cynog-SE0214-Ab-1/ GM-Tg-cynog-SE0214-Ab-2Anti-Cynomolgus/ Rhesus macaque FDCSP monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0214-Ab-1/ GM-Tg-felg-SE0214-Ab-2Anti-Feline FDCSP monoclonal antibodyFeline
GM-Tg-cang-SE0214-Ab-1/ GM-Tg-cang-SE0214-Ab-2Anti-Canine FDCSP monoclonal antibodyCanine
GM-Tg-bovg-SE0214-Ab-1/ GM-Tg-bovg-SE0214-Ab-2Anti-Bovine FDCSP monoclonal antibodyBovine
GM-Tg-equg-SE0214-Ab-1/ GM-Tg-equg-SE0214-Ab-2Anti-Equine FDCSP monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0214-Ab-1/ GM-Tg-hg-SE0214-Ab-2; GM-Tg-rg-SE0214-Ab-1/ GM-Tg-rg-SE0214-Ab-2;
GM-Tg-mg-SE0214-Ab-1/ GM-Tg-mg-SE0214-Ab-2; GM-Tg-cynog-SE0214-Ab-1/ GM-Tg-cynog-SE0214-Ab-2;
GM-Tg-felg-SE0214-Ab-1/ GM-Tg-felg-SE0214-Ab-2; GM-Tg-cang-SE0214-Ab-1/ GM-Tg-cang-SE0214-Ab-2;
GM-Tg-bovg-SE0214-Ab-1/ GM-Tg-bovg-SE0214-Ab-2; GM-Tg-equg-SE0214-Ab-1/ GM-Tg-equg-SE0214-Ab-2
Products NameAnti-FDCSP monoclonal antibody
Formatmab
Target NameFDCSP
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-FDCSP benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0214-Ag-1Recombinant multi-species FDSCP/ FDCSP/ C4orf7 protein


    Target information

    Target IDGM-SE0214
    Target NameFDCSP
    Gene ID260436,494497,494224,707784,104968904,111772689
    Gene Symbol and SynonymsBC037156,C4orf7,C5H4orf7,FDC-SP,FDCSP
    Uniprot AccessionQ8NFU4
    Uniprot Entry NameFDSCP_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000181617
    Target ClassificationN/A

    The target: FDCSP, gene name: FDCSP, also named as C4orf7, FDC-SP. This gene encodes a small secreted protein that is expressed in follicular dendritic cells. This protein specifically binds to activated B cells, and functions as a regulator of antibody responses. It is also thought to contribute to tumor metastases by promoting cancer cell migration and invasion. [provided by RefSeq, Dec 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.