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Anti-FGF19 functional antibody
Anti-FGF19 functional antibody for cell culture, ELISA & in-vivo assay
Go to FGF19/FGF19 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0215-Ab-1/ GM-Tg-hg-SE0215-Ab-2 | Anti-Human FGF19 monoclonal antibody | Human |
| GM-Tg-rg-SE0215-Ab-1/ GM-Tg-rg-SE0215-Ab-2 | Anti-Rat FGF19 monoclonal antibody | Rat |
| GM-Tg-mg-SE0215-Ab-1/ GM-Tg-mg-SE0215-Ab-2 | Anti-Mouse FGF19 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0215-Ab-1/ GM-Tg-cynog-SE0215-Ab-2 | Anti-Cynomolgus/ Rhesus macaque FGF19 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0215-Ab-1/ GM-Tg-felg-SE0215-Ab-2 | Anti-Feline FGF19 monoclonal antibody | Feline |
| GM-Tg-cang-SE0215-Ab-1/ GM-Tg-cang-SE0215-Ab-2 | Anti-Canine FGF19 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0215-Ab-1/ GM-Tg-bovg-SE0215-Ab-2 | Anti-Bovine FGF19 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0215-Ab-1/ GM-Tg-equg-SE0215-Ab-2 | Anti-Equine FGF19 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0215-Ab-1/ GM-Tg-hg-SE0215-Ab-2; GM-Tg-rg-SE0215-Ab-1/ GM-Tg-rg-SE0215-Ab-2; GM-Tg-mg-SE0215-Ab-1/ GM-Tg-mg-SE0215-Ab-2; GM-Tg-cynog-SE0215-Ab-1/ GM-Tg-cynog-SE0215-Ab-2; GM-Tg-felg-SE0215-Ab-1/ GM-Tg-felg-SE0215-Ab-2; GM-Tg-cang-SE0215-Ab-1/ GM-Tg-cang-SE0215-Ab-2; GM-Tg-bovg-SE0215-Ab-1/ GM-Tg-bovg-SE0215-Ab-2; GM-Tg-equg-SE0215-Ab-1/ GM-Tg-equg-SE0215-Ab-2 |
| Products Name | Anti-FGF19 monoclonal antibody |
| Format | mab |
| Target Name | FGF19 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-FGF19 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0215-Ag-1 | Recombinant multi-species FGF19 protein |
| Cytokine | GM-Tg-g-SE0215-Ag-1 | fibroblast growth factor 19 (FGF19) protein |
| ORF Viral Vector | pGMAAV000215 | human FGF19 AAV plasmid |
| ORF Viral Vector | vGMLP004563 | human FGF19 Lentivirus particle |
| ORF Viral Vector | pGMLP004563 | human FGF19 Lentivirus plasmid |
| ORF Viral Vector | vGMAAV000215 | human FGF19 AAV particle |
| ORF Viral Vector | pGMLPm004573 | mouse Fgf15 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm004573 | mouse Fgf15 Lentivirus particle |
Target information
| Target ID | GM-SE0215 |
| Target Name | FGF19 |
| Gene ID | 9965,14170,170582,709109,483681,101087099,521475,100060488 |
| Gene Symbol and Synonyms | Fgf15,FGF19,Fgf8a |
| Uniprot Accession | O95750 |
| Uniprot Entry Name | FGF19_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Cytokine Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000162344 |
| Target Classification | N/A |
The target: FGF19, gene name: FGF19, also named as . The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. This growth factor is a high affinity, heparin dependent ligand for FGFR4. Expression of this gene was detected only in fetal but not adult brain tissue. Synergistic interaction of the chick homolog and Wnt-8c has been shown to be required for initiation of inner ear development. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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