Anti-FUT6/ FCT3A/ FT1A functional antibody

Anti-FUT6/ FCT3A/ FT1A functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to FUT6/FUT6 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0228-Ab-1/ GM-Tg-hg-SE0228-Ab-2Anti-Human FUT6 monoclonal antibodyHuman
GM-Tg-rg-SE0228-Ab-1/ GM-Tg-rg-SE0228-Ab-2Anti-Rat FUT6 monoclonal antibodyRat
GM-Tg-mg-SE0228-Ab-1/ GM-Tg-mg-SE0228-Ab-2Anti-Mouse FUT6 monoclonal antibodyMouse
GM-Tg-cynog-SE0228-Ab-1/ GM-Tg-cynog-SE0228-Ab-2Anti-Cynomolgus/ Rhesus macaque FUT6 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0228-Ab-1/ GM-Tg-felg-SE0228-Ab-2Anti-Feline FUT6 monoclonal antibodyFeline
GM-Tg-cang-SE0228-Ab-1/ GM-Tg-cang-SE0228-Ab-2Anti-Canine FUT6 monoclonal antibodyCanine
GM-Tg-bovg-SE0228-Ab-1/ GM-Tg-bovg-SE0228-Ab-2Anti-Bovine FUT6 monoclonal antibodyBovine
GM-Tg-equg-SE0228-Ab-1/ GM-Tg-equg-SE0228-Ab-2Anti-Equine FUT6 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0228-Ab-1/ GM-Tg-hg-SE0228-Ab-2; GM-Tg-rg-SE0228-Ab-1/ GM-Tg-rg-SE0228-Ab-2;
GM-Tg-mg-SE0228-Ab-1/ GM-Tg-mg-SE0228-Ab-2; GM-Tg-cynog-SE0228-Ab-1/ GM-Tg-cynog-SE0228-Ab-2;
GM-Tg-felg-SE0228-Ab-1/ GM-Tg-felg-SE0228-Ab-2; GM-Tg-cang-SE0228-Ab-1/ GM-Tg-cang-SE0228-Ab-2;
GM-Tg-bovg-SE0228-Ab-1/ GM-Tg-bovg-SE0228-Ab-2; GM-Tg-equg-SE0228-Ab-1/ GM-Tg-equg-SE0228-Ab-2
Products NameAnti-FUT6 monoclonal antibody
Formatmab
Target NameFUT6
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-FUT6 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0228-Ag-1Recombinant multi-species FUT6/ FCT3A/ FT1A protein


    Target information

    Target IDGM-SE0228
    Target NameFUT6
    Gene ID2528,338077
    Gene Symbol and SynonymsFCT3A,FT1A,Fuc-TVI,FucT-VI,FUT,FUT3,FUT5,FUT6,FUTB
    Uniprot AccessionP51993,Q11126
    Uniprot Entry NameFUT6_HUMAN,FUT3_BOVIN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000156413
    Target ClassificationN/A

    The target: FUT6, gene name: FUT6, also named as FCT3A, FT1A, Fuc-TVI, FucT-VI. The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of sialyl-Lewis X, an E-selectin ligand. Mutations in this gene are a cause of fucosyltransferase-6 deficiency. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.