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Anti-G3ST1/ GAL3ST1/ CST functional antibody
Anti-G3ST1/ GAL3ST1/ CST functional antibody for cell culture, ELISA & in-vivo assay
Go to GAL3ST1/GAL3ST1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0229-Ab-1/ GM-Tg-hg-SE0229-Ab-2 | Anti-Human GAL3ST1 monoclonal antibody | Human |
| GM-Tg-rg-SE0229-Ab-1/ GM-Tg-rg-SE0229-Ab-2 | Anti-Rat GAL3ST1 monoclonal antibody | Rat |
| GM-Tg-mg-SE0229-Ab-1/ GM-Tg-mg-SE0229-Ab-2 | Anti-Mouse GAL3ST1 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0229-Ab-1/ GM-Tg-cynog-SE0229-Ab-2 | Anti-Cynomolgus/ Rhesus macaque GAL3ST1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0229-Ab-1/ GM-Tg-felg-SE0229-Ab-2 | Anti-Feline GAL3ST1 monoclonal antibody | Feline |
| GM-Tg-cang-SE0229-Ab-1/ GM-Tg-cang-SE0229-Ab-2 | Anti-Canine GAL3ST1 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0229-Ab-1/ GM-Tg-bovg-SE0229-Ab-2 | Anti-Bovine GAL3ST1 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0229-Ab-1/ GM-Tg-equg-SE0229-Ab-2 | Anti-Equine GAL3ST1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0229-Ab-1/ GM-Tg-hg-SE0229-Ab-2; GM-Tg-rg-SE0229-Ab-1/ GM-Tg-rg-SE0229-Ab-2; GM-Tg-mg-SE0229-Ab-1/ GM-Tg-mg-SE0229-Ab-2; GM-Tg-cynog-SE0229-Ab-1/ GM-Tg-cynog-SE0229-Ab-2; GM-Tg-felg-SE0229-Ab-1/ GM-Tg-felg-SE0229-Ab-2; GM-Tg-cang-SE0229-Ab-1/ GM-Tg-cang-SE0229-Ab-2; GM-Tg-bovg-SE0229-Ab-1/ GM-Tg-bovg-SE0229-Ab-2; GM-Tg-equg-SE0229-Ab-1/ GM-Tg-equg-SE0229-Ab-2 |
| Products Name | Anti-GAL3ST1 monoclonal antibody |
| Format | mab |
| Target Name | GAL3ST1 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-GAL3ST1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0229-Ag-1 | Recombinant multi-species G3ST1/ GAL3ST1/ CST protein |
Target information
| Target ID | GM-SE0229 |
| Target Name | GAL3ST1 |
| Gene ID | 9514,53897,683713,715998,611960,101092797,513295,100063781 |
| Gene Symbol and Synonyms | CST,GAL3ST1,Gcst |
| Uniprot Accession | Q99999,A6QNK1 |
| Uniprot Entry Name | G3ST1_HUMAN,G3ST1_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000128242 |
| Target Classification | N/A |
The target: GAL3ST1, gene name: GAL3ST1, also named as CST. Sulfonation, an important step in the metabolism of many drugs, xenobiotics, hormones, and neurotransmitters, is catalyzed by sulfotransferases. This gene encodes galactosylceramide sulfotransferase, which catalyzes the sulfation of membrane glycolipids including the final step in the synthesis of sulfatide, a major lipid component of the myelin sheath. This gene exhibits elevated expression in ovarian epithelial carcinoma and the encoded enzyme exhibits elevated activity in renal cell carcinoma. Mutations in this gene may be associated with reduced insulin resistance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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