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Anti-G3ST2/ GAL3ST2/ GAL3ST-2 functional antibody
Anti-G3ST2/ GAL3ST2/ GAL3ST-2 functional antibody for cell culture, ELISA & in-vivo assay
Go to GAL3ST2/GAL3ST2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0230-Ab-1/ GM-Tg-hg-SE0230-Ab-2 | Anti-Human GAL3ST2 monoclonal antibody | Human |
| GM-Tg-rg-SE0230-Ab-1/ GM-Tg-rg-SE0230-Ab-2 | Anti-Rat GAL3ST2 monoclonal antibody | Rat |
| GM-Tg-mg-SE0230-Ab-1/ GM-Tg-mg-SE0230-Ab-2 | Anti-Mouse GAL3ST2 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0230-Ab-1/ GM-Tg-cynog-SE0230-Ab-2 | Anti-Cynomolgus/ Rhesus macaque GAL3ST2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0230-Ab-1/ GM-Tg-felg-SE0230-Ab-2 | Anti-Feline GAL3ST2 monoclonal antibody | Feline |
| GM-Tg-cang-SE0230-Ab-1/ GM-Tg-cang-SE0230-Ab-2 | Anti-Canine GAL3ST2 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0230-Ab-1/ GM-Tg-bovg-SE0230-Ab-2 | Anti-Bovine GAL3ST2 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0230-Ab-1/ GM-Tg-equg-SE0230-Ab-2 | Anti-Equine GAL3ST2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0230-Ab-1/ GM-Tg-hg-SE0230-Ab-2; GM-Tg-rg-SE0230-Ab-1/ GM-Tg-rg-SE0230-Ab-2; GM-Tg-mg-SE0230-Ab-1/ GM-Tg-mg-SE0230-Ab-2; GM-Tg-cynog-SE0230-Ab-1/ GM-Tg-cynog-SE0230-Ab-2; GM-Tg-felg-SE0230-Ab-1/ GM-Tg-felg-SE0230-Ab-2; GM-Tg-cang-SE0230-Ab-1/ GM-Tg-cang-SE0230-Ab-2; GM-Tg-bovg-SE0230-Ab-1/ GM-Tg-bovg-SE0230-Ab-2; GM-Tg-equg-SE0230-Ab-1/ GM-Tg-equg-SE0230-Ab-2 |
| Products Name | Anti-GAL3ST2 monoclonal antibody |
| Format | mab |
| Target Name | GAL3ST2 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-GAL3ST2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0230-Ag-1 | Recombinant multi-species G3ST2/ GAL3ST2/ GAL3ST-2 protein |
Target information
| Target ID | GM-SE0230 |
| Target Name | GAL3ST2 |
| Gene ID | 64090,685402,717931,486212,101098323,523830,100067898 |
| Gene Symbol and Synonyms | GAL3ST-2,GAL3ST2,GP3ST |
| Uniprot Accession | Q9H3Q3 |
| Uniprot Entry Name | G3ST2_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000154252 |
| Target Classification | N/A |
The target: GAL3ST2, gene name: GAL3ST2, also named as GAL3ST-2, GP3ST. This gene encodes a member of the galactose-3-O-sulfotransferase protein family. The product of this gene catalyzes sulfonation by transferring a sulfate group to the hydroxyl at C-3 of nonreducing beta-galactosyl residues, and it can act on both type 1 and type 2 (Galbeta 1-3/1-4GlcNAc-R) oligosaccharides with similar efficiencies, and on core 1 glycans. This enzyme has been implicated in tumor metastasis processes. This gene is different from the GAL3ST3 gene located on chromosome 11, which has also been referred to as GAL3ST2 and encodes a related enzyme with distinct tissue distribution and substrate specificities, compared to galactose-3-O-sulfotransferase 2. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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