Anti-GLT10/ GALNT10/ GALNACT10 functional antibody

Anti-GLT10/ GALNT10/ GALNACT10 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to GALNT10/GALNT10 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0232-Ab-1/ GM-Tg-hg-SE0232-Ab-2Anti-Human GALNT10 monoclonal antibodyHuman
GM-Tg-rg-SE0232-Ab-1/ GM-Tg-rg-SE0232-Ab-2Anti-Rat GALNT10 monoclonal antibodyRat
GM-Tg-mg-SE0232-Ab-1/ GM-Tg-mg-SE0232-Ab-2Anti-Mouse GALNT10 monoclonal antibodyMouse
GM-Tg-cynog-SE0232-Ab-1/ GM-Tg-cynog-SE0232-Ab-2Anti-Cynomolgus/ Rhesus macaque GALNT10 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0232-Ab-1/ GM-Tg-felg-SE0232-Ab-2Anti-Feline GALNT10 monoclonal antibodyFeline
GM-Tg-cang-SE0232-Ab-1/ GM-Tg-cang-SE0232-Ab-2Anti-Canine GALNT10 monoclonal antibodyCanine
GM-Tg-bovg-SE0232-Ab-1/ GM-Tg-bovg-SE0232-Ab-2Anti-Bovine GALNT10 monoclonal antibodyBovine
GM-Tg-equg-SE0232-Ab-1/ GM-Tg-equg-SE0232-Ab-2Anti-Equine GALNT10 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0232-Ab-1/ GM-Tg-hg-SE0232-Ab-2; GM-Tg-rg-SE0232-Ab-1/ GM-Tg-rg-SE0232-Ab-2;
GM-Tg-mg-SE0232-Ab-1/ GM-Tg-mg-SE0232-Ab-2; GM-Tg-cynog-SE0232-Ab-1/ GM-Tg-cynog-SE0232-Ab-2;
GM-Tg-felg-SE0232-Ab-1/ GM-Tg-felg-SE0232-Ab-2; GM-Tg-cang-SE0232-Ab-1/ GM-Tg-cang-SE0232-Ab-2;
GM-Tg-bovg-SE0232-Ab-1/ GM-Tg-bovg-SE0232-Ab-2; GM-Tg-equg-SE0232-Ab-1/ GM-Tg-equg-SE0232-Ab-2
Products NameAnti-GALNT10 monoclonal antibody
Formatmab
Target NameGALNT10
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-GALNT10 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0232-Ag-1Recombinant multi-species GLT10/ GALNT10/ GALNACT10 protein


    Target information

    Target IDGM-SE0232
    Target NameGALNT10
    Gene ID55568,171212,170501,714287,489165,101097132,787200,100071405
    Gene Symbol and SynonymsC330012K04Rik,GalNAc-T10,GalNAc-T9,GALNACT10,GALNT10,Galnt9,PPGALNACT10,ppGaNTase,PPGANTASE10
    Uniprot AccessionQ86SR1,Q925R7
    Uniprot Entry NameGLT10_HUMAN,GLT10_RAT
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000164574
    Target ClassificationN/A

    The target: GALNT10, gene name: GALNT10, also named as GALNACT10, PPGALNACT10, PPGANTASE10. This gene encodes a member of the GalNAc polypeptide N-acetylgalactosaminyltransferases. These enzymes catalyze the first step in the synthesis of mucin-type oligosaccharides. These proteins transfer GalNAc from UDP-GalNAc to either serine or threonine residues of polypeptide acceptors. The protein encoded by this locus may have increased catalytic activity toward glycosylated peptides compared to activity toward non-glycosylated peptides.[provided by RefSeq, Apr 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.