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Anti-HMCN1/ ARMD1/ FBLN6 functional antibody
Anti-HMCN1/ ARMD1/ FBLN6 functional antibody for cell culture, ELISA & in-vivo assay
Go to HMCN1/HMCN1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0264-Ab-1/ GM-Tg-hg-SE0264-Ab-2 | Anti-Human HMCN1 monoclonal antibody | Human |
| GM-Tg-rg-SE0264-Ab-1/ GM-Tg-rg-SE0264-Ab-2 | Anti-Rat HMCN1 monoclonal antibody | Rat |
| GM-Tg-mg-SE0264-Ab-1/ GM-Tg-mg-SE0264-Ab-2 | Anti-Mouse HMCN1 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0264-Ab-1/ GM-Tg-cynog-SE0264-Ab-2 | Anti-Cynomolgus/ Rhesus macaque HMCN1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0264-Ab-1/ GM-Tg-felg-SE0264-Ab-2 | Anti-Feline HMCN1 monoclonal antibody | Feline |
| GM-Tg-cang-SE0264-Ab-1/ GM-Tg-cang-SE0264-Ab-2 | Anti-Canine HMCN1 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0264-Ab-1/ GM-Tg-bovg-SE0264-Ab-2 | Anti-Bovine HMCN1 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0264-Ab-1/ GM-Tg-equg-SE0264-Ab-2 | Anti-Equine HMCN1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0264-Ab-1/ GM-Tg-hg-SE0264-Ab-2; GM-Tg-rg-SE0264-Ab-1/ GM-Tg-rg-SE0264-Ab-2; GM-Tg-mg-SE0264-Ab-1/ GM-Tg-mg-SE0264-Ab-2; GM-Tg-cynog-SE0264-Ab-1/ GM-Tg-cynog-SE0264-Ab-2; GM-Tg-felg-SE0264-Ab-1/ GM-Tg-felg-SE0264-Ab-2; GM-Tg-cang-SE0264-Ab-1/ GM-Tg-cang-SE0264-Ab-2; GM-Tg-bovg-SE0264-Ab-1/ GM-Tg-bovg-SE0264-Ab-2; GM-Tg-equg-SE0264-Ab-1/ GM-Tg-equg-SE0264-Ab-2 |
| Products Name | Anti-HMCN1 monoclonal antibody |
| Format | mab |
| Target Name | HMCN1 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-HMCN1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0264-Ag-1 | Recombinant multi-species HMCN1/ ARMD1/ FBLN6 protein |
Target information
| Target ID | GM-SE0264 |
| Target Name | HMCN1 |
| Gene ID | 83872,545370,289094,714026,490318,101083136,521326,100052277 |
| Gene Symbol and Synonyms | ARMD1,EG545370,FBLN6,FIBL-6,FIBL6,Gm201,HMCN1,RGD1564772 |
| Uniprot Accession | Q96RW7 |
| Uniprot Entry Name | HMCN1_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000143341 |
| Target Classification | N/A |
The target: HMCN1, gene name: HMCN1, also named as ARMD1, FBLN6, FIBL-6, FIBL6. This gene encodes a large extracellular member of the immunoglobulin superfamily. A similar protein in C. elegans forms long, fine tracks at specific extracellular sites that are involved in many processes such as stabilization of the germline syncytium, anchorage of mechanosensory neurons to the epidermis, and organization of hemidesmosomes in the epidermis. Mutations in this gene may be associated with age-related macular degeneration. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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