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Anti-HS2ST/ HS2ST1/ dJ604K5.2 functional antibody
Anti-HS2ST/ HS2ST1/ dJ604K5.2 functional antibody for cell culture, ELISA & in-vivo assay
Go to HS2ST1/HS2ST1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0266-Ab-1/ GM-Tg-hg-SE0266-Ab-2 | Anti-Human HS2ST1 monoclonal antibody | Human |
| GM-Tg-rg-SE0266-Ab-1/ GM-Tg-rg-SE0266-Ab-2 | Anti-Rat HS2ST1 monoclonal antibody | Rat |
| GM-Tg-mg-SE0266-Ab-1/ GM-Tg-mg-SE0266-Ab-2 | Anti-Mouse HS2ST1 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0266-Ab-1/ GM-Tg-cynog-SE0266-Ab-2 | Anti-Cynomolgus/ Rhesus macaque HS2ST1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0266-Ab-1/ GM-Tg-felg-SE0266-Ab-2 | Anti-Feline HS2ST1 monoclonal antibody | Feline |
| GM-Tg-cang-SE0266-Ab-1/ GM-Tg-cang-SE0266-Ab-2 | Anti-Canine HS2ST1 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0266-Ab-1/ GM-Tg-bovg-SE0266-Ab-2 | Anti-Bovine HS2ST1 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0266-Ab-1/ GM-Tg-equg-SE0266-Ab-2 | Anti-Equine HS2ST1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0266-Ab-1/ GM-Tg-hg-SE0266-Ab-2; GM-Tg-rg-SE0266-Ab-1/ GM-Tg-rg-SE0266-Ab-2; GM-Tg-mg-SE0266-Ab-1/ GM-Tg-mg-SE0266-Ab-2; GM-Tg-cynog-SE0266-Ab-1/ GM-Tg-cynog-SE0266-Ab-2; GM-Tg-felg-SE0266-Ab-1/ GM-Tg-felg-SE0266-Ab-2; GM-Tg-cang-SE0266-Ab-1/ GM-Tg-cang-SE0266-Ab-2; GM-Tg-bovg-SE0266-Ab-1/ GM-Tg-bovg-SE0266-Ab-2; GM-Tg-equg-SE0266-Ab-1/ GM-Tg-equg-SE0266-Ab-2 |
| Products Name | Anti-HS2ST1 monoclonal antibody |
| Format | mab |
| Target Name | HS2ST1 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-HS2ST1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0266-Ag-1 | Recombinant multi-species HS2ST/ HS2ST1/ dJ604K5.2 protein |
Target information
| Target ID | GM-SE0266 |
| Target Name | HS2ST1 |
| Gene ID | 9653,23908,292155,712540,479963,101080559,523780,100063266 |
| Gene Symbol and Synonyms | 2OST,dJ604K5.2,Hs2st,HS2ST1,mKIAA0448,NFSRA |
| Uniprot Accession | Q7LGA3 |
| Uniprot Entry Name | HS2ST_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000153936 |
| Target Classification | N/A |
The target: HS2ST1, gene name: HS2ST1, also named as dJ604K5.2. Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. This gene encodes a member of the heparan sulfate biosynthetic enzyme family that transfers sulfate to the 2 position of the iduronic acid residue of heparan sulfate. The disruption of this gene resulted in no kidney formation in knockout embryonic mice, indicating that the absence of this enzyme may interfere with the signaling required for kidney formation. Two alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Aug 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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