Anti-IGSF1/ CHTE/ IGCD1 functional antibody

Anti-IGSF1/ CHTE/ IGCD1 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to IGSF1/IGSF1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0283-Ab-1/ GM-Tg-hg-SE0283-Ab-2Anti-Human IGSF1 monoclonal antibodyHuman
GM-Tg-rg-SE0283-Ab-1/ GM-Tg-rg-SE0283-Ab-2Anti-Rat IGSF1 monoclonal antibodyRat
GM-Tg-mg-SE0283-Ab-1/ GM-Tg-mg-SE0283-Ab-2Anti-Mouse IGSF1 monoclonal antibodyMouse
GM-Tg-cynog-SE0283-Ab-1/ GM-Tg-cynog-SE0283-Ab-2Anti-Cynomolgus/ Rhesus macaque IGSF1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0283-Ab-1/ GM-Tg-felg-SE0283-Ab-2Anti-Feline IGSF1 monoclonal antibodyFeline
GM-Tg-cang-SE0283-Ab-1/ GM-Tg-cang-SE0283-Ab-2Anti-Canine IGSF1 monoclonal antibodyCanine
GM-Tg-bovg-SE0283-Ab-1/ GM-Tg-bovg-SE0283-Ab-2Anti-Bovine IGSF1 monoclonal antibodyBovine
GM-Tg-equg-SE0283-Ab-1/ GM-Tg-equg-SE0283-Ab-2Anti-Equine IGSF1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0283-Ab-1/ GM-Tg-hg-SE0283-Ab-2; GM-Tg-rg-SE0283-Ab-1/ GM-Tg-rg-SE0283-Ab-2;
GM-Tg-mg-SE0283-Ab-1/ GM-Tg-mg-SE0283-Ab-2; GM-Tg-cynog-SE0283-Ab-1/ GM-Tg-cynog-SE0283-Ab-2;
GM-Tg-felg-SE0283-Ab-1/ GM-Tg-felg-SE0283-Ab-2; GM-Tg-cang-SE0283-Ab-1/ GM-Tg-cang-SE0283-Ab-2;
GM-Tg-bovg-SE0283-Ab-1/ GM-Tg-bovg-SE0283-Ab-2; GM-Tg-equg-SE0283-Ab-1/ GM-Tg-equg-SE0283-Ab-2
Products NameAnti-IGSF1 monoclonal antibody
Formatmab
Target NameIGSF1
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-IGSF1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0283-Ag-1Recombinant multi-species IGSF1/ CHTE/ IGCD1 protein


    Target information

    Target IDGM-SE0283
    Target NameIGSF1
    Gene ID3547,209268,302822,704264,481051,101084176,100125775,100058129
    Gene Symbol and Synonyms5330413N23,5530402E03,CHTE,IGCD1,IGDC1,IGSF1,INHBP,InhBP/p120,mKIAA0364,p120,PGSF2
    Uniprot AccessionQ8N6C5,Q925N6
    Uniprot Entry NameIGSF1_HUMAN,IGSF1_RAT
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000147255
    Target ClassificationN/A

    The target: IGSF1, gene name: IGSF1, also named as CHTE, IGCD1, IGDC1, INHBP, PGSF2, p120. This gene encodes a member of the immunoglobulin-like domain-containing superfamily. Proteins in this superfamily contain varying numbers of immunoglobulin-like domains and are thought to participate in the regulation of interactions between cells. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.