Anti-PLGT3/ KDELC2 functional antibody

Anti-PLGT3/ KDELC2 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to KDELC2/KDELC2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0293-Ab-1/ GM-Tg-hg-SE0293-Ab-2Anti-Human KDELC2 monoclonal antibodyHuman
GM-Tg-rg-SE0293-Ab-1/ GM-Tg-rg-SE0293-Ab-2Anti-Rat KDELC2 monoclonal antibodyRat
GM-Tg-mg-SE0293-Ab-1/ GM-Tg-mg-SE0293-Ab-2Anti-Mouse KDELC2 monoclonal antibodyMouse
GM-Tg-cynog-SE0293-Ab-1/ GM-Tg-cynog-SE0293-Ab-2Anti-Cynomolgus/ Rhesus macaque KDELC2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0293-Ab-1/ GM-Tg-felg-SE0293-Ab-2Anti-Feline KDELC2 monoclonal antibodyFeline
GM-Tg-cang-SE0293-Ab-1/ GM-Tg-cang-SE0293-Ab-2Anti-Canine KDELC2 monoclonal antibodyCanine
GM-Tg-bovg-SE0293-Ab-1/ GM-Tg-bovg-SE0293-Ab-2Anti-Bovine KDELC2 monoclonal antibodyBovine
GM-Tg-equg-SE0293-Ab-1/ GM-Tg-equg-SE0293-Ab-2Anti-Equine KDELC2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0293-Ab-1/ GM-Tg-hg-SE0293-Ab-2; GM-Tg-rg-SE0293-Ab-1/ GM-Tg-rg-SE0293-Ab-2;
GM-Tg-mg-SE0293-Ab-1/ GM-Tg-mg-SE0293-Ab-2; GM-Tg-cynog-SE0293-Ab-1/ GM-Tg-cynog-SE0293-Ab-2;
GM-Tg-felg-SE0293-Ab-1/ GM-Tg-felg-SE0293-Ab-2; GM-Tg-cang-SE0293-Ab-1/ GM-Tg-cang-SE0293-Ab-2;
GM-Tg-bovg-SE0293-Ab-1/ GM-Tg-bovg-SE0293-Ab-2; GM-Tg-equg-SE0293-Ab-1/ GM-Tg-equg-SE0293-Ab-2
Products NameAnti-KDELC2 monoclonal antibody
Formatmab
Target NameKDELC2
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-KDELC2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0293-Ag-1Recombinant multi-species PLGT3/ KDELC2 protein


    Target information

    Target IDGM-SE0293
    Target NameKDELC2
    Gene ID143888,68304,315664,708097,489419,101099996,100298704,100069813
    Gene Symbol and Synonyms2010004J24Rik,4833410J10Rik,KDELC2,POGLUT3
    Uniprot AccessionQ7Z4H8,Q566E5
    Uniprot Entry NamePLGT3_HUMAN,PLGT3_RAT
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000178202
    Target ClassificationN/A

    The target: KDELC2, gene name: KDELC2, also named as . Enables UDP-glucosyltransferase activity and UDP-xylosyltransferase activity. Involved in protein O-linked glycosylation via serine. Predicted to be located in endoplasmic reticulum lumen. Predicted to be active in endomembrane system. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.