Anti-LRR3C/ LRRC3C functional antibody

Anti-LRR3C/ LRRC3C functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to LRRC3C/LRRC3C products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0320-Ab-1/ GM-Tg-hg-SE0320-Ab-2Anti-Human LRRC3C monoclonal antibodyHuman
GM-Tg-rg-SE0320-Ab-1/ GM-Tg-rg-SE0320-Ab-2Anti-Rat LRRC3C monoclonal antibodyRat
GM-Tg-mg-SE0320-Ab-1/ GM-Tg-mg-SE0320-Ab-2Anti-Mouse LRRC3C monoclonal antibodyMouse
GM-Tg-cynog-SE0320-Ab-1/ GM-Tg-cynog-SE0320-Ab-2Anti-Cynomolgus/ Rhesus macaque LRRC3C monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0320-Ab-1/ GM-Tg-felg-SE0320-Ab-2Anti-Feline LRRC3C monoclonal antibodyFeline
GM-Tg-cang-SE0320-Ab-1/ GM-Tg-cang-SE0320-Ab-2Anti-Canine LRRC3C monoclonal antibodyCanine
GM-Tg-bovg-SE0320-Ab-1/ GM-Tg-bovg-SE0320-Ab-2Anti-Bovine LRRC3C monoclonal antibodyBovine
GM-Tg-equg-SE0320-Ab-1/ GM-Tg-equg-SE0320-Ab-2Anti-Equine LRRC3C monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0320-Ab-1/ GM-Tg-hg-SE0320-Ab-2; GM-Tg-rg-SE0320-Ab-1/ GM-Tg-rg-SE0320-Ab-2;
GM-Tg-mg-SE0320-Ab-1/ GM-Tg-mg-SE0320-Ab-2; GM-Tg-cynog-SE0320-Ab-1/ GM-Tg-cynog-SE0320-Ab-2;
GM-Tg-felg-SE0320-Ab-1/ GM-Tg-felg-SE0320-Ab-2; GM-Tg-cang-SE0320-Ab-1/ GM-Tg-cang-SE0320-Ab-2;
GM-Tg-bovg-SE0320-Ab-1/ GM-Tg-bovg-SE0320-Ab-2; GM-Tg-equg-SE0320-Ab-1/ GM-Tg-equg-SE0320-Ab-2
Products NameAnti-LRRC3C monoclonal antibody
Formatmab
Target NameLRRC3C
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-LRRC3C benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0320-Ag-1Recombinant multi-species LRR3C/ LRRC3C protein


    Target information

    Target IDGM-SE0320
    Target NameLRRC3C
    Gene ID100505591,192852,287668,699290,119876587,101093812,618432,100067960
    Gene Symbol and SynonymsGm12,LRRC3C,RGD1563281
    Uniprot AccessionA6NJW4
    Uniprot Entry NameLRR3C_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000204913
    Target ClassificationN/A

    The target: LRRC3C, gene name: LRRC3C, also named as . Predicted to be integral component of membrane. Predicted to be active in extracellular matrix and extracellular space. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.