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Anti-MGT5A/ MGAT5/ GNT-V functional antibody
Anti-MGT5A/ MGAT5/ GNT-V functional antibody for cell culture, ELISA & in-vivo assay
Go to MGAT5/MGAT5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0347-Ab-1/ GM-Tg-hg-SE0347-Ab-2 | Anti-Human MGAT5 monoclonal antibody | Human |
| GM-Tg-rg-SE0347-Ab-1/ GM-Tg-rg-SE0347-Ab-2 | Anti-Rat MGAT5 monoclonal antibody | Rat |
| GM-Tg-mg-SE0347-Ab-1/ GM-Tg-mg-SE0347-Ab-2 | Anti-Mouse MGAT5 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0347-Ab-1/ GM-Tg-cynog-SE0347-Ab-2 | Anti-Cynomolgus/ Rhesus macaque MGAT5 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0347-Ab-1/ GM-Tg-felg-SE0347-Ab-2 | Anti-Feline MGAT5 monoclonal antibody | Feline |
| GM-Tg-cang-SE0347-Ab-1/ GM-Tg-cang-SE0347-Ab-2 | Anti-Canine MGAT5 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0347-Ab-1/ GM-Tg-bovg-SE0347-Ab-2 | Anti-Bovine MGAT5 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0347-Ab-1/ GM-Tg-equg-SE0347-Ab-2 | Anti-Equine MGAT5 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0347-Ab-1/ GM-Tg-hg-SE0347-Ab-2; GM-Tg-rg-SE0347-Ab-1/ GM-Tg-rg-SE0347-Ab-2; GM-Tg-mg-SE0347-Ab-1/ GM-Tg-mg-SE0347-Ab-2; GM-Tg-cynog-SE0347-Ab-1/ GM-Tg-cynog-SE0347-Ab-2; GM-Tg-felg-SE0347-Ab-1/ GM-Tg-felg-SE0347-Ab-2; GM-Tg-cang-SE0347-Ab-1/ GM-Tg-cang-SE0347-Ab-2; GM-Tg-bovg-SE0347-Ab-1/ GM-Tg-bovg-SE0347-Ab-2; GM-Tg-equg-SE0347-Ab-1/ GM-Tg-equg-SE0347-Ab-2 |
| Products Name | Anti-MGAT5 monoclonal antibody |
| Format | mab |
| Target Name | MGAT5 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-MGAT5 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0347-Ag-1 | Recombinant multi-species MGT5A/ MGAT5/ GNT-V protein |
| ORF Viral Vector | vGMLP001166 | human MGAT5 Lentivirus particle |
| ORF Viral Vector | pGMLP001166 | human MGAT5 Lentivirus plasmid |
| ORF Viral Vector | pGMLV000780 | Norway rat Mgat5 Lentivirus plasmid |
| ORF Viral Vector | vGMLV000780 | Norway rat Mgat5 Lentivirus particle |
Target information
| Target ID | GM-SE0347 |
| Target Name | MGAT5 |
| Gene ID | 4249,107895,65271,709108,101088682,537595,100050356 |
| Gene Symbol and Synonyms | 4930471A21Rik,5330407H02Rik,glcNAc-T V,GlcNAc-TV,GNT-V,GNT-VA,MGAT5,MGAT5A |
| Uniprot Accession | Q09328,Q08834 |
| Uniprot Entry Name | MGT5A_HUMAN,MGT5A_RAT |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000152127 |
| Target Classification | N/A |
The target: MGAT5, gene name: MGAT5, also named as GNT-V, GNT-VAA, MGAT5. The protein encoded by this gene belongs to the glycosyltransferase family. It catalyzes the addition of beta-1,6-N-acetylglucosamine to the alpha-linked mannose of biantennary N-linked oligosaccharides present on the newly synthesized glycoproteins. It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides. Alterations of the oligosaccharides on cell surface glycoproteins cause significant changes in the adhesive or migratory behavior of a cell. Increase in the activity of this enzyme has been correlated with the progression of invasive malignancies. [provided by RefSeq, Oct 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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