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Anti-MMP20/ AI2A2/ MMP-20 functional antibody
Anti-MMP20/ AI2A2/ MMP-20 functional antibody for cell culture, ELISA & in-vivo assay
Go to MMP20/MMP20 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0352-Ab-1/ GM-Tg-hg-SE0352-Ab-2 | Anti-Human MMP20 monoclonal antibody | Human |
| GM-Tg-rg-SE0352-Ab-1/ GM-Tg-rg-SE0352-Ab-2 | Anti-Rat MMP20 monoclonal antibody | Rat |
| GM-Tg-mg-SE0352-Ab-1/ GM-Tg-mg-SE0352-Ab-2 | Anti-Mouse MMP20 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0352-Ab-1/ GM-Tg-cynog-SE0352-Ab-2 | Anti-Cynomolgus/ Rhesus macaque MMP20 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0352-Ab-1/ GM-Tg-felg-SE0352-Ab-2 | Anti-Feline MMP20 monoclonal antibody | Feline |
| GM-Tg-cang-SE0352-Ab-1/ GM-Tg-cang-SE0352-Ab-2 | Anti-Canine MMP20 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0352-Ab-1/ GM-Tg-bovg-SE0352-Ab-2 | Anti-Bovine MMP20 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0352-Ab-1/ GM-Tg-equg-SE0352-Ab-2 | Anti-Equine MMP20 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0352-Ab-1/ GM-Tg-hg-SE0352-Ab-2; GM-Tg-rg-SE0352-Ab-1/ GM-Tg-rg-SE0352-Ab-2; GM-Tg-mg-SE0352-Ab-1/ GM-Tg-mg-SE0352-Ab-2; GM-Tg-cynog-SE0352-Ab-1/ GM-Tg-cynog-SE0352-Ab-2; GM-Tg-felg-SE0352-Ab-1/ GM-Tg-felg-SE0352-Ab-2; GM-Tg-cang-SE0352-Ab-1/ GM-Tg-cang-SE0352-Ab-2; GM-Tg-bovg-SE0352-Ab-1/ GM-Tg-bovg-SE0352-Ab-2; GM-Tg-equg-SE0352-Ab-1/ GM-Tg-equg-SE0352-Ab-2 |
| Products Name | Anti-MMP20 monoclonal antibody |
| Format | mab |
| Target Name | MMP20 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-MMP20 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0352-Ag-1 | Recombinant multi-species MMP20/ AI2A2/ MMP-20 protein |
Target information
| Target ID | GM-SE0352 |
| Target Name | MMP20 |
| Gene ID | 9313,30800,300341,703188,611829,101080734,281916,100061314 |
| Gene Symbol and Synonyms | AI2A2,MMP-20,MMP20 |
| Uniprot Accession | O60882,O18767 |
| Uniprot Entry Name | MMP20_HUMAN,MMP20_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000137674 |
| Target Classification | N/A |
The target: MMP20, gene name: MMP20, also named as AI2A2, MMP-20. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene degrades amelogenin, the major protein component of dental enamel matrix, and thus thought to play a role in tooth enamel formation. A mutation in this gene, which alters the normal splice pattern and results in premature termination of the encoded protein, has been associated with amelogenesis imperfecta. This gene is part of a cluster of MMP genes located on chromosome 11q22.3. [provided by RefSeq, Aug 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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