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Anti-MMP24/ MMP-24/ MMP25 functional antibody
Anti-MMP24/ MMP-24/ MMP25 functional antibody for cell culture, ELISA & in-vivo assay
Go to MMP24/MMP24 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0354-Ab-1/ GM-Tg-hg-SE0354-Ab-2 | Anti-Human MMP24 monoclonal antibody | Human |
| GM-Tg-rg-SE0354-Ab-1/ GM-Tg-rg-SE0354-Ab-2 | Anti-Rat MMP24 monoclonal antibody | Rat |
| GM-Tg-mg-SE0354-Ab-1/ GM-Tg-mg-SE0354-Ab-2 | Anti-Mouse MMP24 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0354-Ab-1/ GM-Tg-cynog-SE0354-Ab-2 | Anti-Cynomolgus/ Rhesus macaque MMP24 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0354-Ab-1/ GM-Tg-felg-SE0354-Ab-2 | Anti-Feline MMP24 monoclonal antibody | Feline |
| GM-Tg-cang-SE0354-Ab-1/ GM-Tg-cang-SE0354-Ab-2 | Anti-Canine MMP24 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0354-Ab-1/ GM-Tg-bovg-SE0354-Ab-2 | Anti-Bovine MMP24 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0354-Ab-1/ GM-Tg-equg-SE0354-Ab-2 | Anti-Equine MMP24 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0354-Ab-1/ GM-Tg-hg-SE0354-Ab-2; GM-Tg-rg-SE0354-Ab-1/ GM-Tg-rg-SE0354-Ab-2; GM-Tg-mg-SE0354-Ab-1/ GM-Tg-mg-SE0354-Ab-2; GM-Tg-cynog-SE0354-Ab-1/ GM-Tg-cynog-SE0354-Ab-2; GM-Tg-felg-SE0354-Ab-1/ GM-Tg-felg-SE0354-Ab-2; GM-Tg-cang-SE0354-Ab-1/ GM-Tg-cang-SE0354-Ab-2; GM-Tg-bovg-SE0354-Ab-1/ GM-Tg-bovg-SE0354-Ab-2; GM-Tg-equg-SE0354-Ab-1/ GM-Tg-equg-SE0354-Ab-2 |
| Products Name | Anti-MMP24 monoclonal antibody |
| Format | mab |
| Target Name | MMP24 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-MMP24 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0354-Ag-1 | Recombinant multi-species MMP24/ MMP-24/ MMP25 protein |
Target information
| Target ID | GM-SE0354 |
| Target Name | MMP24 |
| Gene ID | 10893,17391,83513,712005,485849,101087914,536622,100069462 |
| Gene Symbol and Synonyms | MMP-21,MMP-24,MMP24,MMP25,MT-MMP 5,MT-MMP5,MT5-MMP,MT5MMP,M™MP5 |
| Uniprot Accession | Q9Y5R2,Q99PW6 |
| Uniprot Entry Name | MMP24_HUMAN,MMP24_RAT |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000125966 |
| Target Classification | N/A |
The target: MMP24, gene name: MMP24, also named as MMP-24, MMP25, MT-MMP 5, MT-MMP5, MT5-MMP, MT5MMP, M™MP5. This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. Unlike most MMPs, which are secreted, this protease is a member of the membrane-type MMP (MT-MMP) subfamily, contains a transmembrane domain and is expressed at the cell surface. Substrates of this protease include the proteins cadherin 2 and matrix metallopeptidase 2 (also known as 72 kDa type IV collagenase). The gene has previously been referred to as MMP25 but has been renamed matrix metallopeptidase 24 (MMP24). [provided by RefSeq, Oct 2019].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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