Anti-MPEG1/ MPG1/ MPS1 functional antibody

Anti-MPEG1/ MPG1/ MPS1 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to MPEG1/MPEG1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0356-Ab-1/ GM-Tg-hg-SE0356-Ab-2Anti-Human MPEG1 monoclonal antibodyHuman
GM-Tg-rg-SE0356-Ab-1/ GM-Tg-rg-SE0356-Ab-2Anti-Rat MPEG1 monoclonal antibodyRat
GM-Tg-mg-SE0356-Ab-1/ GM-Tg-mg-SE0356-Ab-2Anti-Mouse MPEG1 monoclonal antibodyMouse
GM-Tg-cynog-SE0356-Ab-1/ GM-Tg-cynog-SE0356-Ab-2Anti-Cynomolgus/ Rhesus macaque MPEG1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0356-Ab-1/ GM-Tg-felg-SE0356-Ab-2Anti-Feline MPEG1 monoclonal antibodyFeline
GM-Tg-cang-SE0356-Ab-1/ GM-Tg-cang-SE0356-Ab-2Anti-Canine MPEG1 monoclonal antibodyCanine
GM-Tg-bovg-SE0356-Ab-1/ GM-Tg-bovg-SE0356-Ab-2Anti-Bovine MPEG1 monoclonal antibodyBovine
GM-Tg-equg-SE0356-Ab-1/ GM-Tg-equg-SE0356-Ab-2Anti-Equine MPEG1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0356-Ab-1/ GM-Tg-hg-SE0356-Ab-2; GM-Tg-rg-SE0356-Ab-1/ GM-Tg-rg-SE0356-Ab-2;
GM-Tg-mg-SE0356-Ab-1/ GM-Tg-mg-SE0356-Ab-2; GM-Tg-cynog-SE0356-Ab-1/ GM-Tg-cynog-SE0356-Ab-2;
GM-Tg-felg-SE0356-Ab-1/ GM-Tg-felg-SE0356-Ab-2; GM-Tg-cang-SE0356-Ab-1/ GM-Tg-cang-SE0356-Ab-2;
GM-Tg-bovg-SE0356-Ab-1/ GM-Tg-bovg-SE0356-Ab-2; GM-Tg-equg-SE0356-Ab-1/ GM-Tg-equg-SE0356-Ab-2
Products NameAnti-MPEG1 monoclonal antibody
Formatmab
Target NameMPEG1
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-MPEG1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0356-Ag-1Recombinant multi-species MPEG1/ MPG1/ MPS1 protein
    ORF Viral VectorpGMLPm003872mouse Mpeg1 Lentivirus plasmid
    ORF Viral VectorvGMLPm003872mouse Mpeg1 Lentivirus particle


    Target information

    Target IDGM-SE0356
    Target NameMPEG1
    Gene ID219972,64552,700274,475960,101098745
    Gene Symbol and SynonymsIMD77,MPEG1,Mpg-1,MPG1,MPS1,P-2
    Uniprot AccessionQ2M385,Q9WV57
    Uniprot Entry NameMPEG1_HUMAN,MPEG1_RAT
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000197629
    Target ClassificationN/A

    The target: MPEG1, gene name: MPEG1, also named as MPG1, MPS1, Mpg-1. Involved in defense response to Gram-negative bacterium and defense response to Gram-positive bacterium. Located in cytoplasmic vesicle. Implicated in primary immunodeficiency disease. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.