Anti-MXRA5 functional antibody

Anti-MXRA5 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to MXRA5/MXRA5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0358-Ab-1/ GM-Tg-hg-SE0358-Ab-2Anti-Human MXRA5 monoclonal antibodyHuman
GM-Tg-rg-SE0358-Ab-1/ GM-Tg-rg-SE0358-Ab-2Anti-Rat MXRA5 monoclonal antibodyRat
GM-Tg-mg-SE0358-Ab-1/ GM-Tg-mg-SE0358-Ab-2Anti-Mouse MXRA5 monoclonal antibodyMouse
GM-Tg-cynog-SE0358-Ab-1/ GM-Tg-cynog-SE0358-Ab-2Anti-Cynomolgus/ Rhesus macaque MXRA5 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0358-Ab-1/ GM-Tg-felg-SE0358-Ab-2Anti-Feline MXRA5 monoclonal antibodyFeline
GM-Tg-cang-SE0358-Ab-1/ GM-Tg-cang-SE0358-Ab-2Anti-Canine MXRA5 monoclonal antibodyCanine
GM-Tg-bovg-SE0358-Ab-1/ GM-Tg-bovg-SE0358-Ab-2Anti-Bovine MXRA5 monoclonal antibodyBovine
GM-Tg-equg-SE0358-Ab-1/ GM-Tg-equg-SE0358-Ab-2Anti-Equine MXRA5 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0358-Ab-1/ GM-Tg-hg-SE0358-Ab-2; GM-Tg-rg-SE0358-Ab-1/ GM-Tg-rg-SE0358-Ab-2;
GM-Tg-mg-SE0358-Ab-1/ GM-Tg-mg-SE0358-Ab-2; GM-Tg-cynog-SE0358-Ab-1/ GM-Tg-cynog-SE0358-Ab-2;
GM-Tg-felg-SE0358-Ab-1/ GM-Tg-felg-SE0358-Ab-2; GM-Tg-cang-SE0358-Ab-1/ GM-Tg-cang-SE0358-Ab-2;
GM-Tg-bovg-SE0358-Ab-1/ GM-Tg-bovg-SE0358-Ab-2; GM-Tg-equg-SE0358-Ab-1/ GM-Tg-equg-SE0358-Ab-2
Products NameAnti-MXRA5 monoclonal antibody
Formatmab
Target NameMXRA5
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-MXRA5 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0358-Ag-1Recombinant multi-species MXRA5 protein


    Target information

    Target IDGM-SE0358
    Target NameMXRA5
    Gene ID25878,706214,491721,101080687,786844,100063681
    Gene Symbol and SynonymsMXRA5
    Uniprot AccessionQ9NR99
    Uniprot Entry NameMXRA5_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseOvary Cancer
    Gene EnsemblENSG00000101825
    Target ClassificationN/A

    The target: MXRA5, gene name: MXRA5, also named as . This gene encodes one of the matrix-remodelling associated proteins. This protein contains 7 leucine-rich repeats and 12 immunoglobulin-like C2-type domains related to perlecan. This gene has a pseudogene on chromosome Y. [provided by RefSeq, Mar 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.