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Anti-NDUB5/ NDUFB5/ CISGDH functional antibody
Anti-NDUB5/ NDUFB5/ CISGDH functional antibody for cell culture, ELISA & in-vivo assay
Go to NDUFB5/NDUFB5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0363-Ab-1/ GM-Tg-hg-SE0363-Ab-2 | Anti-Human NDUFB5 monoclonal antibody | Human |
| GM-Tg-rg-SE0363-Ab-1/ GM-Tg-rg-SE0363-Ab-2 | Anti-Rat NDUFB5 monoclonal antibody | Rat |
| GM-Tg-mg-SE0363-Ab-1/ GM-Tg-mg-SE0363-Ab-2 | Anti-Mouse NDUFB5 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0363-Ab-1/ GM-Tg-cynog-SE0363-Ab-2 | Anti-Cynomolgus/ Rhesus macaque NDUFB5 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0363-Ab-1/ GM-Tg-felg-SE0363-Ab-2 | Anti-Feline NDUFB5 monoclonal antibody | Feline |
| GM-Tg-cang-SE0363-Ab-1/ GM-Tg-cang-SE0363-Ab-2 | Anti-Canine NDUFB5 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0363-Ab-1/ GM-Tg-bovg-SE0363-Ab-2 | Anti-Bovine NDUFB5 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0363-Ab-1/ GM-Tg-equg-SE0363-Ab-2 | Anti-Equine NDUFB5 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0363-Ab-1/ GM-Tg-hg-SE0363-Ab-2; GM-Tg-rg-SE0363-Ab-1/ GM-Tg-rg-SE0363-Ab-2; GM-Tg-mg-SE0363-Ab-1/ GM-Tg-mg-SE0363-Ab-2; GM-Tg-cynog-SE0363-Ab-1/ GM-Tg-cynog-SE0363-Ab-2; GM-Tg-felg-SE0363-Ab-1/ GM-Tg-felg-SE0363-Ab-2; GM-Tg-cang-SE0363-Ab-1/ GM-Tg-cang-SE0363-Ab-2; GM-Tg-bovg-SE0363-Ab-1/ GM-Tg-bovg-SE0363-Ab-2; GM-Tg-equg-SE0363-Ab-1/ GM-Tg-equg-SE0363-Ab-2 |
| Products Name | Anti-NDUFB5 monoclonal antibody |
| Format | mab |
| Target Name | NDUFB5 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-NDUFB5 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0363-Ag-1 | Recombinant multi-species NDUB5/ NDUFB5/ CISGDH protein |
Target information
| Target ID | GM-SE0363 |
| Target Name | NDUFB5 |
| Gene ID | 4711,66046,294964,708821,478639,101090177,338061,100058402 |
| Gene Symbol and Synonyms | 0610007D05Rik,CI-SGDH,CISGDH,NDUFB5,SGDH |
| Uniprot Accession | O43674,Q02380 |
| Uniprot Entry Name | NDUB5_HUMAN,NDUB5_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000136521 |
| Target Classification | N/A |
The target: NDUFB5, gene name: NDUFB5, also named as CISGDH, SGDH. The protein encoded by this gene is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I). Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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