Anti-NINJ1/ NIN1/ NINJURIN functional antibody

Anti-NINJ1/ NIN1/ NINJURIN functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to NINJ1/NINJ1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0369-Ab-1/ GM-Tg-hg-SE0369-Ab-2Anti-Human NINJ1 monoclonal antibodyHuman
GM-Tg-rg-SE0369-Ab-1/ GM-Tg-rg-SE0369-Ab-2Anti-Rat NINJ1 monoclonal antibodyRat
GM-Tg-mg-SE0369-Ab-1/ GM-Tg-mg-SE0369-Ab-2Anti-Mouse NINJ1 monoclonal antibodyMouse
GM-Tg-cynog-SE0369-Ab-1/ GM-Tg-cynog-SE0369-Ab-2Anti-Cynomolgus/ Rhesus macaque NINJ1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0369-Ab-1/ GM-Tg-felg-SE0369-Ab-2Anti-Feline NINJ1 monoclonal antibodyFeline
GM-Tg-cang-SE0369-Ab-1/ GM-Tg-cang-SE0369-Ab-2Anti-Canine NINJ1 monoclonal antibodyCanine
GM-Tg-bovg-SE0369-Ab-1/ GM-Tg-bovg-SE0369-Ab-2Anti-Bovine NINJ1 monoclonal antibodyBovine
GM-Tg-equg-SE0369-Ab-1/ GM-Tg-equg-SE0369-Ab-2Anti-Equine NINJ1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0369-Ab-1/ GM-Tg-hg-SE0369-Ab-2; GM-Tg-rg-SE0369-Ab-1/ GM-Tg-rg-SE0369-Ab-2;
GM-Tg-mg-SE0369-Ab-1/ GM-Tg-mg-SE0369-Ab-2; GM-Tg-cynog-SE0369-Ab-1/ GM-Tg-cynog-SE0369-Ab-2;
GM-Tg-felg-SE0369-Ab-1/ GM-Tg-felg-SE0369-Ab-2; GM-Tg-cang-SE0369-Ab-1/ GM-Tg-cang-SE0369-Ab-2;
GM-Tg-bovg-SE0369-Ab-1/ GM-Tg-bovg-SE0369-Ab-2; GM-Tg-equg-SE0369-Ab-1/ GM-Tg-equg-SE0369-Ab-2
Products NameAnti-NINJ1 monoclonal antibody
Formatmab
Target NameNINJ1
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-NINJ1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0369-Ag-1Recombinant multi-species NINJ1/ NIN1/ NINJURIN protein
    ORF Viral VectorvGMAD000163human NINJ1 Adenovirus particle
    ORF Viral VectorpGMAD000163human NINJ1 Adenovirus plasmid
    ORF Viral VectorpGMAD000259mouse Ninj1 Adenovirus plasmid
    ORF Viral VectorvGMAD000259mouse Ninj1 Adenovirus particle


    Target information

    Target IDGM-SE0369
    Target NameNINJ1
    Gene ID4814,18081,25338,717218,610587,101092405,511468,100146796
    Gene Symbol and SynonymsNIN1,NINJ1,NINJURIN,ninjurin-1
    Uniprot AccessionQ92982,P70617
    Uniprot Entry NameNINJ1_HUMAN,NINJ1_RAT
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000131669
    Target ClassificationN/A

    The target: NINJ1, gene name: NINJ1, also named as NIN1, NINJURIN. The ninjurin protein is upregulated after nerve injury both in dorsal root ganglion neurons and in Schwann cells (Araki and Milbrandt, 1996 [PubMed 8780658]). It demonstrates properties of a homophilic adhesion molecule and promotes neurite outgrowth from primary cultured dorsal root ganglion neurons.[supplied by OMIM, Aug 2009].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.