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Anti-NPTXR/ NPR functional antibody
Anti-NPTXR/ NPR functional antibody for cell culture, ELISA & in-vivo assay
Go to NPTXR/NPTXR products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0374-Ab-1/ GM-Tg-hg-SE0374-Ab-2 | Anti-Human NPTXR monoclonal antibody | Human |
| GM-Tg-rg-SE0374-Ab-1/ GM-Tg-rg-SE0374-Ab-2 | Anti-Rat NPTXR monoclonal antibody | Rat |
| GM-Tg-mg-SE0374-Ab-1/ GM-Tg-mg-SE0374-Ab-2 | Anti-Mouse NPTXR monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0374-Ab-1/ GM-Tg-cynog-SE0374-Ab-2 | Anti-Cynomolgus/ Rhesus macaque NPTXR monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0374-Ab-1/ GM-Tg-felg-SE0374-Ab-2 | Anti-Feline NPTXR monoclonal antibody | Feline |
| GM-Tg-cang-SE0374-Ab-1/ GM-Tg-cang-SE0374-Ab-2 | Anti-Canine NPTXR monoclonal antibody | Canine |
| GM-Tg-bovg-SE0374-Ab-1/ GM-Tg-bovg-SE0374-Ab-2 | Anti-Bovine NPTXR monoclonal antibody | Bovine |
| GM-Tg-equg-SE0374-Ab-1/ GM-Tg-equg-SE0374-Ab-2 | Anti-Equine NPTXR monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0374-Ab-1/ GM-Tg-hg-SE0374-Ab-2; GM-Tg-rg-SE0374-Ab-1/ GM-Tg-rg-SE0374-Ab-2; GM-Tg-mg-SE0374-Ab-1/ GM-Tg-mg-SE0374-Ab-2; GM-Tg-cynog-SE0374-Ab-1/ GM-Tg-cynog-SE0374-Ab-2; GM-Tg-felg-SE0374-Ab-1/ GM-Tg-felg-SE0374-Ab-2; GM-Tg-cang-SE0374-Ab-1/ GM-Tg-cang-SE0374-Ab-2; GM-Tg-bovg-SE0374-Ab-1/ GM-Tg-bovg-SE0374-Ab-2; GM-Tg-equg-SE0374-Ab-1/ GM-Tg-equg-SE0374-Ab-2 |
| Products Name | Anti-NPTXR monoclonal antibody |
| Format | mab |
| Target Name | NPTXR |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-NPTXR benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0374-Ag-1 | Recombinant multi-species NPTXR/ NPR protein |
Target information
| Target ID | GM-SE0374 |
| Target Name | NPTXR |
| Gene ID | 23467,73340,81005,100428434,100685212,102900025,100848095,102149998 |
| Gene Symbol and Synonyms | 1200009K17Rik,1700036C17Rik,5730406O18Rik,D15Bwg0580e,Npcd,NPR,NPTXR |
| Uniprot Accession | O95502,O35764 |
| Uniprot Entry Name | NPTXR_HUMAN,NPTXR_RAT |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000221890 |
| Target Classification | N/A |
The target: NPTXR, gene name: NPTXR, also named as NPR. This gene encodes a protein similar to the rat neuronal pentraxin receptor. The rat pentraxin receptor is an integral membrane protein that is thought to mediate neuronal uptake of the snake venom toxin, taipoxin, and its transport into the synapses. Studies in rat indicate that translation of this mRNA initiates at a non-AUG (CUG) codon. This may also be true for mouse and human, based on strong sequence conservation amongst these species. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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