Anti-5NT3A/ NT5C3A/ NT5C3 functional antibody

Anti-5NT3A/ NT5C3A/ NT5C3 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to NT5C3A/NT5C3A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0376-Ab-1/ GM-Tg-hg-SE0376-Ab-2Anti-Human NT5C3A monoclonal antibodyHuman
GM-Tg-rg-SE0376-Ab-1/ GM-Tg-rg-SE0376-Ab-2Anti-Rat NT5C3A monoclonal antibodyRat
GM-Tg-mg-SE0376-Ab-1/ GM-Tg-mg-SE0376-Ab-2Anti-Mouse NT5C3A monoclonal antibodyMouse
GM-Tg-cynog-SE0376-Ab-1/ GM-Tg-cynog-SE0376-Ab-2Anti-Cynomolgus/ Rhesus macaque NT5C3A monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0376-Ab-1/ GM-Tg-felg-SE0376-Ab-2Anti-Feline NT5C3A monoclonal antibodyFeline
GM-Tg-cang-SE0376-Ab-1/ GM-Tg-cang-SE0376-Ab-2Anti-Canine NT5C3A monoclonal antibodyCanine
GM-Tg-bovg-SE0376-Ab-1/ GM-Tg-bovg-SE0376-Ab-2Anti-Bovine NT5C3A monoclonal antibodyBovine
GM-Tg-equg-SE0376-Ab-1/ GM-Tg-equg-SE0376-Ab-2Anti-Equine NT5C3A monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0376-Ab-1/ GM-Tg-hg-SE0376-Ab-2; GM-Tg-rg-SE0376-Ab-1/ GM-Tg-rg-SE0376-Ab-2;
GM-Tg-mg-SE0376-Ab-1/ GM-Tg-mg-SE0376-Ab-2; GM-Tg-cynog-SE0376-Ab-1/ GM-Tg-cynog-SE0376-Ab-2;
GM-Tg-felg-SE0376-Ab-1/ GM-Tg-felg-SE0376-Ab-2; GM-Tg-cang-SE0376-Ab-1/ GM-Tg-cang-SE0376-Ab-2;
GM-Tg-bovg-SE0376-Ab-1/ GM-Tg-bovg-SE0376-Ab-2; GM-Tg-equg-SE0376-Ab-1/ GM-Tg-equg-SE0376-Ab-2
Products NameAnti-NT5C3A monoclonal antibody
Formatmab
Target NameNT5C3A
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-NT5C3A benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0376-Ag-1Recombinant multi-species 5NT3A/ NT5C3A/ NT5C3 protein
    ORF Viral VectorvGMLP004815human NT5C3A Lentivirus particle
    ORF Viral VectorpGMLP004815human NT5C3A Lentivirus plasmid
    ORF Viral VectorpGMLPm001330mouse Nt5c3 Lentivirus plasmid
    ORF Viral VectorvGMLPm001330mouse Nt5c3 Lentivirus particle


    Target information

    Target IDGM-SE0376
    Target NameNT5C3A
    Gene ID51251,107569,312373,708743,475277,101091271,511858,100055382
    Gene Symbol and Synonyms1600024P05Rik,2610206B05Rik,3110004A18Rik,cN-III,hUMP1,lupin,NT5C3,NT5C3A,Nt5y,p36,P5'N-1,P5N-1,PN-1,PN-I,POMP,PSN1,UMPH,Umph-1,UMPH1
    Uniprot AccessionQ9H0P0
    Uniprot Entry Name5NT3A_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000122643
    Target ClassificationN/A

    The target: NT5C3A, gene name: NT5C3A, also named as NT5C3, P5'N-1, P5N-1, PN-I, POMP, PSN1, UMPH, UMPH1, cN-III, hUMP1, p36. This gene encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. The encoded protein is the type 1 isozyme of pyrimidine 5' nucleotidase and catalyzes the dephosphorylation of pyrimidine 5' monophosphates. Mutations in this gene are a cause of hemolytic anemia due to uridine 5-prime monophosphate hydrolase deficiency. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and pseudogenes of this gene are located on the long arm of chromosomes 3 and 4. [provided by RefSeq, Mar 2012].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.